MPH-220
Modify Date: 2025-08-27 07:40:10
MPH-220 structure
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Common Name | MPH-220 | ||
|---|---|---|---|---|
| CAS Number | 2649776-79-2 | Molecular Weight | 383.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H21N3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MPH-220MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness[1]. |
| Name | MPH-220 |
|---|
| Description | MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness[1]. |
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| Related Catalog | |
| In Vitro | MPH-220 (0-50 µM) 抑制人肌肉肌球蛋白样品中肌动蛋白激活的 ATP 酶活性[1]。 |
| In Vivo | MPH-220 (25-30 mg/kg，腹腔注射或口服灌胃) 可降低麻醉大鼠的骨骼肌力量，而不会影响心血管[1]。 MPH-220 (15 mg/kg，口服) 改善脑损伤大鼠的步态功能[1]。 Animal Model: Anesthetized rats[1] Dosage: 25-30 mg/kg Administration: Intraperitoneal injection (i.p.) or oral gavage Result: Reduced skeletal muscle force. Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle. |
| References |
| Molecular Formula | C20H21N3O3S |
|---|---|
| Molecular Weight | 383.46 |