KRAS G12C inhibitor 18

Modify Date: 2024-01-09 19:01:44

KRAS G12C inhibitor 18 structure	Common Name	KRAS G12C inhibitor 18
	CAS Number	2649788-45-2	Molecular Weight	510.97
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₀ClFN₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS G12C inhibitor 18

KRAS G12C inhibitor 18 is a potent and orally active KRAS G12C inhibitor. Anti-tumor activities[1].

Name	KRAS G12C inhibitor 18

Description	KRAS G12C inhibitor 18 is a potent and orally active KRAS G12C inhibitor. Anti-tumor activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C
In Vitro	KRAS G12C inhibitor 18 (compound 34) inhibits the growth of many KRas G12C mutant tumor cell lines (such as H358, SW1436, MiaPaca-2 cells, etc.)[1].
In Vivo	KRAS G12C inhibitor 18 exhibits a dose dependent inhibiton of pERK and active KRas after a single dose treatment from 12.5 to 100 mg/kg at 8 hours[1]. KRAS G12C inhibitor 18 (30 mg/kg; p.o.; twice daily) exhibits anti-tumor growth activity in lung cancer H358 xenograft mouse model[1].
References	[1]. Serge Louis Boulet, et al. Kras g12c inhibitors. WO2021118877A1.

Molecular Formula	C₂₅H₂₀ClFN₄O₃S
Molecular Weight	510.97

DC Chemicals Limited
China
Product Name: KRAS G12C inhibitor 18
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

KRAS G12C inhibitor 18 suppliers

KRAS G12C inhibitor 18 price