KRAS G12C inhibitor 23

Modify Date: 2025-08-24 18:41:55

KRAS G12C inhibitor 23 Structure
KRAS G12C inhibitor 23 structure
Common Name KRAS G12C inhibitor 23
CAS Number 2735721-00-1 Molecular Weight 553.63
Density N/A Boiling Point N/A
Molecular Formula C32H32FN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KRAS G12C inhibitor 23


KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1)[1].

 Names

Name KRAS G12C inhibitor 23

 KRAS G12C inhibitor 23 Biological Activity

Description KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1)[1].
Related Catalog
Target

KRas G12C

References

[1]. Fused ring compound and application thereof in medicine. WO2021218939A1.

 Chemical & Physical Properties

Molecular Formula C32H32FN5O3
Molecular Weight 553.63
InChIKey UWIDMHGDYVIUOQ-FQEVSTJZSA-N
SMILES C=CC(=O)N1CCN(c2nc(=O)n(-c3c(C)ccnc3C(C)C)c3c4c(c(F)cc23)-c2ccccc2CO4)C(C)C1
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