Ryuvidine
Modify Date: 2024-01-27 15:45:48
Ryuvidine structure
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Common Name | Ryuvidine | ||
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| CAS Number | 265312-55-8 | Molecular Weight | 284.33300 | |
| Density | 1.416g/cm3 | Boiling Point | 463.8ºC at 760 mmHg | |
| Molecular Formula | C15H12N2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 234.3ºC | |
Use of RyuvidineRyuvidine is a potent inhibitor of SET domain-containing protein 8(SETD8) with an IC50 of 0.5 µM and suppresses monomethylation of H4K20 in vitro[1]. Ryuvidine also inhibits CDK4 with an IC50 of 6.0 μM and is cytotoxic against a range of human cancer cells[2]. |
| Name | Ryuvidine,2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione |
|---|---|
| Synonym | More Synonyms |
| Description | Ryuvidine is a potent inhibitor of SET domain-containing protein 8(SETD8) with an IC50 of 0.5 µM and suppresses monomethylation of H4K20 in vitro[1]. Ryuvidine also inhibits CDK4 with an IC50 of 6.0 μM and is cytotoxic against a range of human cancer cells[2]. |
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| Related Catalog | |
| Target |
CDK4:6.0 μM (IC50) |
| References |
| Density | 1.416g/cm3 |
|---|---|
| Boiling Point | 463.8ºC at 760 mmHg |
| Molecular Formula | C15H12N2O2S |
| Molecular Weight | 284.33300 |
| Flash Point | 234.3ºC |
| Exact Mass | 284.06200 |
| PSA | 87.30000 |
| LogP | 3.20790 |
| Vapour Pressure | 8.83E-09mmHg at 25°C |
| Index of Refraction | 1.707 |
| Ryuvidine |