PROTAC MEK1 Degrader-1

Modify Date: 2024-01-28 18:39:20

PROTAC MEK1 Degrader-1 structure	Common Name	PROTAC MEK1 Degrader-1
	CAS Number	2671004-41-2	Molecular Weight	1201.17
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₃H₆₆FIN₈O₁₁S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC MEK1 Degrader-1

PROTAC MEK1 Degrader-1 is a PROTAC targeting MEK1 with a pIC50 value of 7.0. PROTAC MEK1 Degrader-1 consists of a MEK1 inhibitor and a von Hippel-Lindau ligand. PROTAC MEK1 Degrader-1 can inhibit ERK1/2 phosphorylation. PROTAC MEK1 Degrader-1 shows an antiproliferative activity against A375 cells[1].

Name	PROTAC MEK1 Degrader-1

Description	PROTAC MEK1 Degrader-1 is a PROTAC targeting MEK1 with a pIC50 value of 7.0. PROTAC MEK1 Degrader-1 consists of a MEK1 inhibitor and a von Hippel-Lindau ligand. PROTAC MEK1 Degrader-1 can inhibit ERK1/2 phosphorylation. PROTAC MEK1 Degrader-1 shows an antiproliferative activity against A375 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> MEK Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
References	[1]. Vollmer S, et al. Design, Synthesis, and Biological Evaluation of MEK PROTACs. J Med Chem. 2020 Jan 9;63(1):157-162.

Molecular Formula	C₅₃H₆₆FIN₈O₁₁S₂
Molecular Weight	1201.17

PROTAC MEK1 Degrader-1

Use of PROTAC MEK1 Degrader-1

Names

PROTAC MEK1 Degrader-1 Biological Activity

Chemical & Physical Properties