Autophagy inducer 2

Modify Date: 2024-01-12 08:25:33

Autophagy inducer 2 Structure
Autophagy inducer 2 structure
Common Name Autophagy inducer 2
CAS Number 2684238-37-5 Molecular Weight 650.94
Density N/A Boiling Point N/A
Molecular Formula C41H58N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Autophagy inducer 2


Autophagy inducer 2 (Compound 11i) is a potent autophagy inducer. Autophagy inducer 2 exhibits apparent antiproliferative activity against the MCF-7 cell line with an IC50 value of 1.31 μM and remarkably inhibits the colony formation of the MCF-7 cells. Autophagy inducer 2 arrests the MCF-7 cells in the G2/M phase by regulating the cell-cycle-related proteins Cdk-1 and Cyclin B1. Autophagy inducer 2 has the potential for the research of breast cancer[1].

 Names

Name Autophagy inducer 2

 Autophagy inducer 2 Biological Activity

Description Autophagy inducer 2 (Compound 11i) is a potent autophagy inducer. Autophagy inducer 2 exhibits apparent antiproliferative activity against the MCF-7 cell line with an IC50 value of 1.31 μM and remarkably inhibits the colony formation of the MCF-7 cells. Autophagy inducer 2 arrests the MCF-7 cells in the G2/M phase by regulating the cell-cycle-related proteins Cdk-1 and Cyclin B1. Autophagy inducer 2 has the potential for the research of breast cancer[1].
Related Catalog
References

[1]. Feng Y, et al. Scaffold hopping of celastrol provides derivatives containing pepper ring, pyrazine and oxazole substructures as potent autophagy inducers against breast cancer cell line MCF-7. Eur J Med Chem. 2022;234:114254.

 Chemical & Physical Properties

Molecular Formula C41H58N6O
Molecular Weight 650.94
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