ER-001259851-000

Modify Date: 2024-04-02 22:18:47

ER-001259851-000 Structure
ER-001259851-000 structure
Common Name ER-001259851-000
CAS Number 2685738-33-2 Molecular Weight 668.774
Density N/A Boiling Point N/A
Molecular Formula C36H41FN8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ER-001259851-000


ER-001259851-000 is a potent, selective, orally active Axl inhibitor with IC50 of 5.2 nM in cell free assays, displays >35-fold selectivity against Mer (IC50=190 nM).ER-001259851-000 shows a promising pharmacokinetic profile in mice.

 Names

Name ER-001259851-000

 ER-001259851-000 Biological Activity

Description ER-001259851-000 is a potent, selective, orally active Axl inhibitor with IC50 of 5.2 nM in cell free assays, displays >35-fold selectivity against Mer (IC50=190 nM).ER-001259851-000 shows a promising pharmacokinetic profile in mice.
References 1. Satoshi Inoue, et al. Bioorg Med Chem Lett. 2021 Sep 15;48:128247.

 Chemical & Physical Properties

Molecular Formula C36H41FN8O4
Molecular Weight 668.774