SAH-13C10

Modify Date: 2024-01-05 16:45:13

SAH-13C10 structure	Common Name	SAH-13C10
	CAS Number	2687960-02-5	Molecular Weight	394.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₁₃C₁₀H₂₀N₆O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SAH-13C10

SAH-13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].

Name	SAH-13C10

Description	SAH-13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. DE LA HABA G, et al. The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine. J Biol Chem. 1959 Mar;234(3):603-8. [3]. Li F, et al. A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5. Biomol Screen. 2016 Mar21(3):290-7.

Molecular Formula	C₄₁₃C₁₀H₂₀N₆O₅S
Molecular Weight	394.34

SAH-13C10

Use of SAH-13C10

Names

SAH-13C10 Biological Activity

Chemical & Physical Properties