C12 NBD Globotriaosylceramide

Modify Date: 2024-01-22 21:16:09

C12 NBD Globotriaosylceramide Structure
C12 NBD Globotriaosylceramide structure
 Common Name C12 NBD Globotriaosylceramide
CAS Number 2692623-26-8 Molecular Weight 1146.32
Density N/A Boiling Point N/A
Molecular Formula C54H91N5O21 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of C12 NBD Globotriaosylceramide


C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside[1].

 Names

Name C12 NBD Globotriaosylceramide

 C12 NBD Globotriaosylceramide Biological Activity

Description C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside[1].
Related Catalog
In Vitro C12 NBD globotriaosylceramide accumulates in human umbilical vascular endothelial cells (HUVECs) treated with the α-galactosidase A inhibitor in a concentration-dependent manner[2].
References

[1]. Kassiani Kytidou, et al. Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease. J Biol Chem. 2018 Jun 29;293(26):10042-10058.

[2]. Janet Hsu, et al. Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. J Control Release. 2011 Feb 10;149(3):323-31.

 Chemical & Physical Properties

Molecular Formula C54H91N5O21
Molecular Weight 1146.32
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