ht-2 toxin

Modify Date: 2024-01-10 10:44:32

ht-2 toxin structure	Common Name	ht-2 toxin
	CAS Number	26934-87-2	Molecular Weight	424.485
	Density	1.3±0.1 g/cm3	Boiling Point	537.1±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	179.8±23.6 °C

Use of ht-2 toxin

HT-2 Toxin is an active, deacetylated metabolite of the T-2 toxin. HT-2 toxin inhibits protein synthesis and cell proliferation in plants[1][2].

Name	ht-2 toxin
Synonym	More Synonyms

Description	HT-2 Toxin is an active, deacetylated metabolite of the T-2 toxin. HT-2 toxin inhibits protein synthesis and cell proliferation in plants[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Nathanail, A.V., et al. Metabolism of the fusarium mycotoxins T-2 toxin and HT-2 toxin in wheat J.Agric.Food Chem 63(35), 7862-7872 (2015). [2]. Berthiller, F., et al. Masked mycotoxins: A review Mol.Nutr.Food Res. 57, 165-186 (2013).

Description

HT-2 Toxin is an active, deacetylated metabolite of the T-2 toxin. HT-2 toxin inhibits protein synthesis and cell proliferation in plants[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

References

[1]. Nathanail, A.V., et al. Metabolism of the fusarium mycotoxins T-2 toxin and HT-2 toxin in wheat J.Agric.Food Chem 63(35), 7862-7872 (2015).

[2]. Berthiller, F., et al. Masked mycotoxins: A review Mol.Nutr.Food Res. 57, 165-186 (2013).

Density	1.3±0.1 g/cm3
Boiling Point	537.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₃₂O₈
Molecular Weight	424.485
Flash Point	179.8±23.6 °C
Exact Mass	424.209717
PSA	114.82000
LogP	2.27
Vapour Pressure	0.0±3.2 mmHg at 25°C
Index of Refraction	1.562
Storage condition	−20°C

ht-2 toxin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YD0050000

CHEMICAL NAME :: Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 15-acetate, 8-isovalerate

CAS REGISTRY NUMBER :: 26934-87-2

LAST UPDATED :: 199306

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C22-H32-O8

MOLECULAR WEIGHT :: 424.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,923,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 52 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Behavioral - ataxia

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,923,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,191,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 46,2613,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Blood - hemorrhage

REFERENCE :: DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 7220 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Behavioral - muscle weakness Behavioral - food intake (animal)

REFERENCE :: AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 35,636,1978

Hazard Codes	T+,T,Xn,F
Risk Phrases	26/27/28-36/37/38-36-20/21/22-11
Safety Phrases	22-26-36/37/39-45-36/37-16
RIDADR	UN 3462 6.1/PG 1
WGK Germany	3
RTECS	YD0050000
Packaging Group	I
Hazard Class	6.1(a)

3α-(2-tetrahydr...

CAS#:108947-27-9

ht-2 toxin

CAS#:26934-87-2

Literature: Wani, Mansukh C.; Rector, Douglas H.; Cook, C. Edgar Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3468 - 3470

12-epi-3α-[(tet...

CAS#:106454-34-6

ht-2 toxin

CAS#:26934-87-2

Literature: Wani, Mansukh C.; Rector, Douglas H.; Cook, C. Edgar Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3468 - 3470

12,13-epoxy-4β-...

CAS#:77620-42-9

ht-2 toxin

CAS#:26934-87-2

Literature: Wani, Mansukh C.; Rector, Douglas H.; Cook, C. Edgar Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3468 - 3470

3-Methylbutanoi...

CAS#:503-74-2

ht-2 toxin

CAS#:26934-87-2

Literature: Wani, Mansukh C.; Rector, Douglas H.; Cook, C. Edgar Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3468 - 3470

Precursor 3
CAS#:503-74-2 3-Methylbutanoi... CAS#:106454-34-6 12-epi-3α-[(tet... CAS#:77620-42-9 12,13-epoxy-4β-...
DownStream 0

HT-2

T-2,Toxin analog

Butanoic acid, 3-methyl-, (2α,3α,4β,6β,8β,11β,12α)-15-(acetyloxy)-12,13-epoxy-3,4-dihydroxytrichothec-9-en-8-yl ester

valerate

Toxin HT 2

(3β,4α,8α)-15-Acetoxy-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate

(3α,4β,8α)-15-(acetyloxy)-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate

Pentanoic acid anion

Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate (8CI)

Mycotoxin HT 2

12,13-Epoxytrichothec-9-ene-3-α,4-β,8-α,15-tetrol 15-acetate 8-isovalerate

ht-2toxin solution

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ht-2 toxin
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: ht-2 toxin
Price: ￥10758.0/5mg ￥2458.0/1mg
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

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