DL-4-FluoroglutaMic acid
DL-4-FluoroglutaMic acid structure
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Common Name | DL-4-FluoroglutaMic acid | ||
|---|---|---|---|---|
| CAS Number | 2708-77-2 | Molecular Weight | 165.12000 | |
| Density | 1.498 g/cm3 | Boiling Point | 342.4ºC at 760 mmHg | |
| Molecular Formula | C5H8FNO4 | Melting Point | 185°C (dec.) | |
| MSDS | Chinese USA | Flash Point | 160.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of DL-4-FluoroglutaMic acid4-Fluoro-DL-glutamic acid is a glutamic acid derivative[1]. |
Summary: 4-Fluoro-dl-glutamic acid (Chinese name: 4-氟-DL-谷氨酸，CAS number: 2708-77-2), molecular formula: C5H8FNO4, molecular weight: 165.12, melting point: 185°C (dec.). For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-fluoro-dl-glutamic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 4-Fluoro-DL-glutamic acid is a glutamic acid derivative[1]. |
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| Related Catalog | |
| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.498 g/cm3 |
|---|---|
| Boiling Point | 342.4ºC at 760 mmHg |
| Melting Point | 185°C (dec.) |
| Molecular Formula | C5H8FNO4 |
| Molecular Weight | 165.12000 |
| Flash Point | 160.9ºC |
| Exact Mass | 165.04400 |
| PSA | 100.62000 |
| Vapour Pressure | 1.37E-05mmHg at 25°C |
| Index of Refraction | 1.491 |
| InChIKey | JPSHPWJJSVEEAX-UHFFFAOYSA-N |
| SMILES | NC(CC(F)C(=O)O)C(=O)O |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2922499990 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~84%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Tolman, V.; Vlasakova, V.; Nemecek, J. Journal of Fluorine Chemistry, 1993 , vol. 60, # 2.3 p. 185 - 191 |
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~81%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Tolman, V. Journal of Fluorine Chemistry, 1993 , vol. 60, # 2.3 p. 179 - 183 |
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~%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Tolman,V.; Veres,K. Tetrahedron Letters, 1966 , p. 3909 - 3912 |
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~%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Alekseewa,L.V. et al. J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, p. 1754 - 1755,1671 - 1672 |
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~%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Alekseewa,L.V. et al. J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, p. 1754 - 1755,1671 - 1672 |
|
~%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Tolman,V.; Veres,K. Tetrahedron Letters, 1966 , p. 3909 - 3912 |
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~%
DL-4-Fluoroglut... CAS#:2708-77-2 |
| Literature: Bergmann,E.D.; Chun-Hsu,L. Synthesis, 1973 , p. 44 - 46 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
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| DownStream 1 | |
CAS#:32563-24-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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4-[18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: synthesis and in vitro characterization.
J. Med. Chem. 54(1) , 406-10, (2011) There is a high demand for tumor specific PET tracers in oncology imaging. Besides glucose, certain amino acids also serve as energy sources and anabolic precursors for tumors. Therefore, (18)F-labele... |
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Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production.
Appl. Environ. Microbiol. 73(14) , 4491-8, (2007) Corynebacterium glutamicum is a biotin auxotroph that secretes L-glutamic acid in response to biotin limitation; this process is employed in industrial L-glutamic acid production. Fatty acid ester sur... |
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Vitamin K-dependent carboxylation. Study of the hydrogen abstraction stereochemistry with gamma-fluoroglutamic acid-containing peptides.
J. Biol. Chem. 258(13) , 7897-9, (1983) Two pentapeptides Phe-Leu-X-Glu-Val where X is either the L-threo-gamma-fluoroglutamic acid or the L-erythro-isomer have been synthesized and tested as substrates in the vitamin K-dependent carboxylat... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Fluoro-2-aminopentanedioic acid |
| 2-Amino-4-fluoropentane-1,5-dioic acid |
| EINECS 220-302-8 |
| 4-Fluoro-Glutamic Acid |
| threo-4-fluoroglutamic acid |
| D,L-erythro,threo-4-fluoroglutamic acid |
| H-4-F-DL-Glu-OH |
| erythro-4-fluoroglutamic acid |
| DL-erythro-4-fluoroglutamic acid |
| DL-4-FLUOROGLUTAMIC ACID |
| MFCD00055778 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for 4-fluoro-dl-glutamic acid? |
| A: Safety information for 4-fluoro-dl-glutamic acid: S26. |
| Q: What are the upstream materials of 4-fluoro-dl-glutamic acid? |
| A: Related upstream materials(CAS) of 4-fluoro-dl-glutamic acid: 1652-64-8;57357-57-0;7682-53-3;23115-42-6;685-88-1. |
| Q: What is the InChIKey of 4-fluoro-dl-glutamic acid? |
| A: InChIKey of 4-fluoro-dl-glutamic acid is JPSHPWJJSVEEAX-UHFFFAOYSA-N. |
| Q: What is the boiling point of 4-fluoro-dl-glutamic acid? |
| A: Boiling point of 4-fluoro-dl-glutamic acid is 342.4ºC at 760 mmHg. |
| Q: What is the melting point of 4-fluoro-dl-glutamic acid? |
| A: Melting point of 4-fluoro-dl-glutamic acid is 185°C (dec.). |
| Q: What is the molecular weight of 4-fluoro-dl-glutamic acid? |
| A: Molecular weight of 4-fluoro-dl-glutamic acid is 165.12000. |
| Q: What is the molecular formula of 4-fluoro-dl-glutamic acid? |
| A: Molecular formula of 4-fluoro-dl-glutamic acid is C5H8FNO4. |
| Q: What are the downstream products of 4-fluoro-dl-glutamic acid? |
| A: Related downstream products(CAS) of 4-fluoro-dl-glutamic acid: 32563-24-9. |
| Q: What are the uses of 4-fluoro-dl-glutamic acid? |
| A: Main uses of 4-fluoro-dl-glutamic acid: 4-Fluoro-DL-glutamic acid is a glutamic acid derivative[1]. |
| Q: What is the polar surface area (PSA) of 4-fluoro-dl-glutamic acid? |
| A: Polar surface area (PSA) of 4-fluoro-dl-glutamic acid is 100.62000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |