D-(+)-Bupivacaine

Modify Date: 2025-08-25 21:06:17

D-(+)-Bupivacaine structure	Common Name	D-(+)-Bupivacaine
	CAS Number	27262-45-9	Molecular Weight	288.428
	Density	1.0±0.1 g/cm3	Boiling Point	423.4±45.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₂₈N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	209.9±28.7 °C

Name	dextrobupivacaine
Synonym	More Synonyms

Density	1.0±0.1 g/cm3
Boiling Point	423.4±45.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₈N₂O
Molecular Weight	288.428
Flash Point	209.9±28.7 °C
Exact Mass	288.220154
PSA	32.34000
LogP	3.64
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.547

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TK6080000

CHEMICAL NAME :: 2',6'-Pipecoloxylidide, 1-butyl-, D-(+)-

CAS REGISTRY NUMBER :: 27262-45-9

LAST UPDATED :: 199112

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C18-H28-N2-O

MOLECULAR WEIGHT :: 288.48

WISWESSER LINE NOTATION :: T6NTJ A4 BVMR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 38 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 31,273,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 31,273,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 31,273,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 31,273,1972

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5500 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 31,273,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,78,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intratracheal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,78,1976

HS Code	2933399090

Precursor 0
DownStream 1
CAS#:14252-80-3 Bupivacaine hyd...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, (2R)-

(R)-(+)-BUPIVACAINE

(2R)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide

(2R)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide

(+)-Bupivacaine

(+)-(R)-Bupivacaine

(R)-Bupivacaine

Bupivacaine Impurity 2

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Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Precursor & DownStream

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.