EGFR-IN-30

Modify Date: 2023-01-16 16:25:35

EGFR-IN-30 structure	Common Name	EGFR-IN-30
	CAS Number	2726463-68-7	Molecular Weight	610.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₃BrN₇O₂P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-30

EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, <1 nM for EGFR (WT), EGFR (L858R/T790M/C797S), respectively. EGFR-IN-30 has potential for cell proliferative diseases, such as cancer research[1].

Name	EGFR-IN-30

Description	EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, <1 nM for EGFR (WT), EGFR (L858R/T790M/C797S), respectively. EGFR-IN-30 has potential for cell proliferative diseases, such as cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR (WT):1-10 nM (IC50) EGFR (L858R/T790M/C797S):<1 nM (IC50)
In Vitro	EGFR-IN-30 (compound 27) inhibits A431 cell (IC50=100-1000 nM),Ba/F3_L858R/T790M/C797S cell (IC50<10 nM), Ba/F3_Del19/T790M/C797S cell (IC50<10 nM)[1].
References	[1]. Shansong Zheng, et al. Tricyclic compounds as EGFR inhibitors. WO2021208918A1.

Molecular Formula	C₂₈H₃₃BrN₇O₂P
Molecular Weight	610.49

DC Chemicals Limited
China
Product Name: EGFR-IN-30
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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