Imidazo[1,2-a]pyridine

Modify Date: 2025-08-20 17:44:31

Imidazo[1,2-a]pyridine Structure
Imidazo[1,2-a]pyridine structure
 Common Name Imidazo[1,2-a]pyridine
CAS Number 274-76-0 Molecular Weight 118.136
Density 1.1±0.1 g/cm3 Boiling Point 103ºC (1 mmHg)
Molecular Formula C7H6N2 Melting Point N/A
MSDS Chinese USA Flash Point 113ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Names

Name Imidazo[1,2-a]pyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 103ºC (1 mmHg)
Molecular Formula C7H6N2
Molecular Weight 118.136
Flash Point 113ºC
Exact Mass 118.053101
PSA 17.30000
LogP 1.35
Appearance of Characters Powder | White to off-white
Index of Refraction 1.628
InChIKey UTCSSFWDNNEEBH-UHFFFAOYSA-N
SMILES c1ccn2ccnc2c1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles28

More Articles
Conversion of pyridine to imidazo[1,2-a]pyridines by copper-catalyzed aerobic dehydrogenative cyclization with oxime esters.

Org. Lett. 15(24) , 6254-7, (2013)

A rapid and environmentally friendly conversion of pyridine to imidazo[1,2-a]pyridines has been developed via copper-catalyzed aerobic dehydrogenative cyclization with ketone oxime esters.

One-pot three-component synthesis of 3-nitro-2-arylimidazo[1,2-a]pyridine derivatives using air as an oxidant.

Chem. Asian J. 7(9) , 2028-31, (2012)

Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.

Bioorg. Med. Chem. 15(1) , 403-12, (2007)

3-{1-[(4-Fluorophenyl)sulfonyl]-1H-pyrazol-3-yl}-2-methylimidazo[1,2-a]pyridine, 2a, was discovered in our chemical library as a novel p110alpha inhibitor with an IC(50) of 0.67microM, through screeni...

 Imidazo[1,2-a]pyridineBioassay

View more

Name: Selectivity index, ratio of CC50 for human HepG2 cells to IC50 for Leishmania donovan...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2444092
Name: Displacement of Y-27632 from ROCK-1 assessed as drop in intensity of binding signals ...
Source: ChEMBL
Target: Rho-associated protein kinase 1
External Id: CHEMBL1647663
Name: Displacement of [3H]-NECA from A2A receptor in rat striatal membrane in presence of A...
Source: ChEMBL
Target: Adenosine receptor A2a
External Id: CHEMBL4058588
Name: Displacement of [3H]-DPCPX from A1 receptor in rat whole brain membrane
Source: ChEMBL
Target: Adenosine receptor A1
External Id: CHEMBL4058587
Name: Lipophilicity, log D of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL4415146
Name: Dissociation constant, pKa of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL863765
Name: Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate at 20 uM preincu...
Source: ChEMBL
Target: Receptor-type tyrosine-protein kinase FLT3
External Id: CHEMBL3420605
Name: Partition coefficient, log P of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL4415147
Name: Distribution coefficient, log D at pH 7.4
Source: ChEMBL
Target: N/A
External Id: CHEMBL863769
Name: Antimicrobial activity against Leishmania donovani MHOM/IN/00/DEVI promastigotes afte...
Source: ChEMBL
Target: Leishmania donovani
External Id: CHEMBL2444096
Total 13, Current Page 1 of 2
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 Synonyms

1H-imidazo[1,2-a]pyridine
imidazo[1,2-a]-pyridine
imidazo[2,1-b]pyridine
Imidazo[1,2-a]pyridine
MFCD00005553
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