acetophenazine

Modify Date: 2024-01-02 17:08:38

acetophenazine structure	Common Name	acetophenazine
	CAS Number	2751-68-0	Molecular Weight	411.56000
	Density	1.203g/cm3	Boiling Point	608.7ºC at 760mmHg
	Molecular Formula	C₂₃H₂₉N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	321.9ºC

Use of acetophenazine

Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].

Name	acetophenazine
Synonym	More Synonyms

Description	Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D2 Receptor
In Vivo	Acetophenazine (2.4 mg/kg; i.h.; single dosage) significantly prolongs the time lapse from the first fight to submission and the actual fighting time to submission in mice[3]. Animal Model: C57BL mice (10-12 weeks)[3] Dosage: 2.4 mg/kg Administration: i.h.; single dosage Result: Significantly prolonged the time lapse from the first fight to submission and the actual fighting time to submission.
References	[1]. Azam Bazrafshan, et al. Acetophenazine versus chlorpromazine for schizophrenia. Cochrane Database of Systematic Reviews. 2015, Issue 4. [2]. Hollister LE, et al. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24(3):273-8. [3]. KNIGHT WR, HOLTZ JR, SPROGIS GR. ACETOPHENAZINE AND FIGHTING BEHAVIOR IN MICE. Science. 1963 Aug 30;141(3583):830-1.

Density	1.203g/cm3
Boiling Point	608.7ºC at 760mmHg
Molecular Formula	C₂₃H₂₉N₃O₂S
Molecular Weight	411.56000
Flash Point	321.9ºC
Exact Mass	411.19800
PSA	72.32000
LogP	3.43270
Vapour Pressure	7.83E-16mmHg at 25°C
Index of Refraction	1.615

Hazard Codes	Xn

1-(10-{3-[4-(2-hydroxy-ethyl)-piperazino]-propyl}-phenothiazin-2-yl)-ethanone

Acetophenazinum [INN-Latin]

1-(10-{3-[4-(2-Hydroxy-aethyl)-piperazino]-propyl}-phenothiazin-2-yl)-aethanon

10-<3-(1-(2-Hydroxy-aethyl)-piperazinyl-(4))-propyl>-2-acetyl-phenothiazin

2-acetyl-10-(-3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl)phenothiazine

Acetophenazinum

1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]ethanone

Acetophenazina [INN-Spanish]

ACETOPHENAZINE

Acephenazinum

Tindal

1-(10-{3-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-propyl}-10H-phenothiazin-2-yl)-ethanone

Acetophenazine [INN]

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ACETOPHENAZINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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