ACETOPHENAZINE

Modify Date: 2024-01-02 14:13:55

ACETOPHENAZINE structure	Common Name	ACETOPHENAZINE
	CAS Number	5714-00-1	Molecular Weight	527.63200
	Density	N/A	Boiling Point	608.7ºC at 760 mmHg
	Molecular Formula	C₂₇H₃₃N₃O₆S	Melting Point	167-168.5°
	MSDS	N/A	Flash Point	321.9ºC
	Symbol	GHS07	Signal Word	Warning

Use of ACETOPHENAZINE

Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression[1].

Name	acetophenazine dimaleate
Synonym	More Synonyms

Description	Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Hollister LE, et al. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24(3):273-8.

Boiling Point	608.7ºC at 760 mmHg
Melting Point	167-168.5°
Molecular Formula	C₂₇H₃₃N₃O₆S
Molecular Weight	527.63200
Flash Point	321.9ºC
Exact Mass	527.20900
PSA	146.92000
LogP	3.14450

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OB4180000

CHEMICAL NAME :: Ketone, 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenot hiazin-2-yl methyl, dimaleate

CAS REGISTRY NUMBER :: 5714-00-1

LAST UPDATED :: 199706

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C23-H29-N3-O2-S.2C4-H4-O4

MOLECULAR WEIGHT :: 643.77

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 14,250,1956 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 415 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,11,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,11,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 39 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,11,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 71 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01100

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 *** REVIEWS *** TOXICOLOGY REVIEW IDPYAK Industrial Pharmacology. (Mount Kisco, NY) V.1-3, 1974-79. Discontinued. Volume(issue)/page/year: 1,203,1974

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Phrases	36
Safety Phrases	26
RIDADR	NONH for all modes of transport
RTECS	OB4180000

[CLINICAL OBSERVATIONS ON THE ACTION OF TINDAL IN PSYCHIATRIC TREATMENT].

Neurol. Neurochir. Psychiatr. Pol. 14 , 683-6, (1964)

Synergism of combined lithium-neuroleptic therapy: a double-blind, placebo-controlled case study.

Am. J. Psychiatry 138(1) , 81-3, (1981)

The authors describe a longitudinal, placebo-controlled study of the response to drug treatment of a 62-year-old schizoaffective patient hospitalized for 40 years. While neither lithium nor a neurolep...

HEMODYNAMIC EFFECTS OF IMIPRAMINE, ACETOPHENAZINE, AND TRIFLUOPERAZINE IN GERIATRIC PSYCHIATRY.

Dis. Nerv. Syst. 26 , 427-9, (1965)

sch6673

acetophenazinemaleate

Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (Z) 2-butenedioate (1_2) (salt)

Acetophazine maleate

ACETOPHENZAINEMALEATE

tindal

Acetophenazine dimaleate

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ACETOPHENAZINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Price: ￥1320/10 mM * 1 mL in DMSO

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ACETOPHENAZINE

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