KRAS G12D inhibitor 3 TFA

Modify Date: 2025-09-26 19:51:25

KRAS G12D inhibitor 3 TFA Structure
KRAS G12D inhibitor 3 TFA structure
Common Name KRAS G12D inhibitor 3 TFA
CAS Number 2757095-12-6 Molecular Weight 748.11
Density N/A Boiling Point N/A
Molecular Formula C36H32ClF6N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KRAS G12D inhibitor 3 TFA


KRAS G12D inhibitor 3 TFA is a KRAS G12D inhibitor with an IC50 of <500 nM. KRAS G12D inhibitor 3 TFA has antitumor effects (WO2022002102A1; compound 146)[1].

 Names

Name KRAS G12D inhibitor 3 TFA

 KRAS G12D inhibitor 3 TFA Biological Activity

Description KRAS G12D inhibitor 3 TFA is a KRAS G12D inhibitor with an IC50 of <500 nM. KRAS G12D inhibitor 3 TFA has antitumor effects (WO2022002102A1; compound 146)[1].
Related Catalog
Target

KRas G12D:<500 nM (IC50)

References

[1]. Xing DAI, et al. Quinazoline compounds, preparation methods and uses thereof. WO2022002102A1.

 Chemical & Physical Properties

Molecular Formula C36H32ClF6N5O4
Molecular Weight 748.11
InChIKey TWEQBEFABPHLAR-RCKNTVAISA-N
SMILES C#Cc1c(F)ccc2cc(OC(=O)C(F)(F)F)cc(-c3c(Cl)cc4c(N5CC6CCC(C5)N6)nc(OCC56CCCN5CC(F)C6)nc4c3F)c12
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