Trk-IN-9
Modify Date: 2025-11-26 09:59:53
Trk-IN-9 structure
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Common Name | Trk-IN-9 | ||
|---|---|---|---|---|
| CAS Number | 2758623-12-8 | Molecular Weight | 454.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H24ClFN6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Trk-IN-9Trk-IN-9 (Compound 12) is a potent inhibitor of TRK. Trk-IN-9 inhibits the proliferation of Km-12 cell lines. Trk-IN-9 induces the apoptosis of Km-12 cells in a concentration-dependent manner. Trk-IN-9 inhibits the phosphorylation of TRK to block downstream pathways. Trk-IN-9 has the potential for the research of NTRK-fusion cancers[1]. |
| Name | Trk-IN-9 |
|---|
| Description | Trk-IN-9 (Compound 12) is a potent inhibitor of TRK. Trk-IN-9 inhibits the proliferation of Km-12 cell lines. Trk-IN-9 induces the apoptosis of Km-12 cells in a concentration-dependent manner. Trk-IN-9 inhibits the phosphorylation of TRK to block downstream pathways. Trk-IN-9 has the potential for the research of NTRK-fusion cancers[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C23H24ClFN6O |
|---|---|
| Molecular Weight | 454.93 |
| InChIKey | DUAIEVYTIKHMGW-LJQANCHMSA-N |
| SMILES | O=C(NC1CCCNC1)c1cccc(Nc2ncc(Cl)c(NCc3cccc(F)c3)n2)c1 |
| Storage condition | -20°C |