Zharp2-1

Modify Date: 2025-11-26 01:54:10

Zharp2-1 Structure
Zharp2-1 structure
Common Name Zharp2-1
CAS Number 2772600-18-5 Molecular Weight 383.40
Density N/A Boiling Point N/A
Molecular Formula C19H18N3O2PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zharp2-1


Zharp2-1 is an oral effective RIPK2 inhibitor, highly associated with inflammatory bowel disease (IBD). Zharp2-1 blocker muramyl dipeptide (MDP) induces growth of mononuclear cells and induces inflammatory cell factor infection. Zharp2-1 attenuates MDP-induced small inguinal peritonitis, or ameliorates by DNBS-induced large inguinal conjunctivitis[1].

 Names

Name Zharp2-1

 Zharp2-1 Biological Activity

Description Zharp2-1 is an oral effective RIPK2 inhibitor, highly associated with inflammatory bowel disease (IBD). Zharp2-1 blocker muramyl dipeptide (MDP) induces growth of mononuclear cells and induces inflammatory cell factor infection. Zharp2-1 attenuates MDP-induced small inguinal peritonitis, or ameliorates by DNBS-induced large inguinal conjunctivitis[1].
Related Catalog
Target

RIPK2[1]

References

[1]. Lai Y, et al. Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease. Biochem Pharmacol. 2023 Aug;214:115647.  

 Chemical & Physical Properties

Molecular Formula C19H18N3O2PS
Molecular Weight 383.40
InChIKey SCBFIYRRWCWQAT-UHFFFAOYSA-N
SMILES COc1cc2nccc(Nc3ccc4scnc4c3)c2cc1P(C)(C)=O
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