AZD5462
Modify Date: 2024-07-20 19:18:06
AZD5462 structure
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Common Name | AZD5462 | ||
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| CAS Number | 2787501-83-9 | Molecular Weight | 544.65 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H41FN2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZD5462AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties[1]. |
| Name | AZD5462 |
|---|
| Description | AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties[1]. |
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| Related Catalog | |
| Target |
RXFP1[1] |
| In Vitro | AZD5462 (example 1) shows stimulatory activity on cAMP or cGMP production with EC50s of 17 nM and 50 nM, respectively[1]. AZD5462 binds human plasma protein with fraction unbound (free) rate of 4.3%, and shows the stability with Clint values of 23 μL/min/mg (human licer microsomal), 4.8 μL/min/106 cells (human hepatocyte), and 11 μL/min/106 cells (rat hepatocyte)[1]. AZD5462 enhances phosphorylation of ERK with an EC50 value of 6.3 nM[1]. |
| References |
| Molecular Formula | C30H41FN2O6 |
|---|---|
| Molecular Weight | 544.65 |