2,6-Difluorophenol

Modify Date: 2024-01-02 13:02:50

2,6-Difluorophenol Structure
2,6-Difluorophenol structure
Common Name 2,6-Difluorophenol
CAS Number 28177-48-2 Molecular Weight 130.092
Density 1.4±0.1 g/cm3 Boiling Point 157.6±0.0 °C at 760 mmHg
Molecular Formula C6H4F2O Melting Point 38-41 °C(lit.)
MSDS Chinese USA Flash Point 58.9±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name 2,6-Difluorophenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 157.6±0.0 °C at 760 mmHg
Melting Point 38-41 °C(lit.)
Molecular Formula C6H4F2O
Molecular Weight 130.092
Flash Point 58.9±0.0 °C
Exact Mass 130.023026
PSA 20.23000
LogP 1.98
Vapour Pressure 2.1±0.3 mmHg at 25°C
Index of Refraction 1.496
Storage condition 2-8°C

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H228-H315-H319-H335
Precautionary Statements P210-P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes F:Flammable
Risk Phrases R11;R36/37/38
Safety Phrases S26
RIDADR UN 1325 4.1/PG 2
WGK Germany 3
Packaging Group II
Hazard Class 4.1
HS Code 2908199090

 Synthetic Route

~62%

2,6-Difluorophenol Structure

2,6-Difluorophenol

CAS#:28177-48-2

Literature: Bracegirdle, Sonia; Anderson, Edward A. Chemical Communications, 2010 , vol. 46, # 20 p. 3454 - 3456

~%

2,6-Difluorophenol Structure

2,6-Difluorophenol

CAS#:28177-48-2

Literature: Finger et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97

~70%

2,6-Difluorophenol Structure

2,6-Difluorophenol

CAS#:28177-48-2

Literature: Moonen, Marielle J. H.; Westphal, Adrie H.; Rietjens, Ivonne M. C. M.; Van Berkel, Willem J. H. Advanced Synthesis and Catalysis, 2005 , vol. 347, # 7-8 p. 1027 - 1034

~%

2,6-Difluorophenol Structure

2,6-Difluorophenol

CAS#:28177-48-2

Literature: Yang, Yong Gang; Chen; Tang; Wen Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2002 , vol. 373, p. 1 - 15

~%

2,6-Difluorophenol Structure

2,6-Difluorophenol

CAS#:28177-48-2

Literature: Roe,A.M. et al. Journal of Medicinal Chemistry, 1968 , vol. 11, # 4 p. 814 - 819

 Customs

HS Code 2908199090
Summary HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

 Articles3

More Articles
Analysis of the association of cobalt(III) chelates with fluorine-containing phenols in supercritical carbon dioxide.

Talanta 146 , 789-94, (2015)

The solubilities of several cobalt(III) chelates (CoL3) with in supercritical carbon dioxide (SC-CO2) were investigated in the presence of fluorine- and trifluoromethyl-substituted phenols (PhOH) usin...

2,6-Difluorophenol as a bioisostere of a carboxylic acid: bioisosteric analogues of gamma-aminobutyric acid.

J. Med. Chem. 42(2) , 329-32, (1999)

3-(Aminomethyl)-2,6-difluorophenol (6) and 4-(aminomethyl)-2, 6-difluorophenol (7) were synthesized in eight and four steps, respectively, starting from 2,6-difluorophenol, to test the potential of th...

Oxidative Polymerization of 2,6-Difluorophenol to Crystalline Poly(2,6-difluoro-1,4-phenylene oxide). Ikeda R, et al.

Macromolecules 33(18) , 6648-52, (2000)

 Synonyms

Phenol, 2,6-difluoro-
QR BF FF
2,6-Difluoro phenol
MFCD00002158
2,6-Difluor-phenol
2,6-F2C6H3OH
EINECS 248-884-9
2,6-Difluorophenol
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