2-Chloro-4-nitrophenol

Modify Date: 2024-01-02 05:10:47

2-Chloro-4-nitrophenol Structure
2-Chloro-4-nitrophenol structure
Common Name 2-Chloro-4-nitrophenol
CAS Number 619-08-9 Molecular Weight 173.554
Density 1.6±0.1 g/cm3 Boiling Point 290.6±25.0 °C at 760 mmHg
Molecular Formula C6H4ClNO3 Melting Point 106 °C
MSDS Chinese USA Flash Point 129.6±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Chloro-4-nitrophenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 290.6±25.0 °C at 760 mmHg
Melting Point 106 °C
Molecular Formula C6H4ClNO3
Molecular Weight 173.554
Flash Point 129.6±23.2 °C
Exact Mass 172.987976
PSA 66.05000
LogP 2.22
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.627
Water Solubility slightly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SK5075000
CHEMICAL NAME :
Phenol, 2-chloro-4-nitro-
CAS REGISTRY NUMBER :
619-08-9
BEILSTEIN REFERENCE NO. :
2046372
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H4-Cl-N-O3
MOLECULAR WEIGHT :
173.56
WISWESSER LINE NOTATION :
WNR DQ CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570573
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570573

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR 2811
WGK Germany 3
RTECS SK5075000
HS Code 29089000

 Synthetic Route

 Customs

HS Code 2908999090
Summary 2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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 Synonyms

2-Chloro-4-nitrophenol
Phenol, 2-chloro-4-nitro-
3-Carboxybenzaldehyde
EINECS 210-578-8
MFCD00043910
2-Chlor-4-nitrobenzolol