Futoquinol

Modify Date: 2024-01-23 20:00:06

Futoquinol Structure
Futoquinol structure
Common Name Futoquinol
CAS Number 28178-92-9 Molecular Weight 354.396
Density 1.2±0.1 g/cm3 Boiling Point 515.0±50.0 °C at 760 mmHg
Molecular Formula C21H22O5 Melting Point N/A
MSDS N/A Flash Point 225.5±30.2 °C

 Use of Futoquinol


Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities[1].

 Names

Name 4-[(E)-1-(1,3-benzodioxol-5-yl)prop-1-en-2-yl]-4,5-dimethoxy-2-prop-2-enylcyclohexa-2,5-dien-1-one
Synonym More Synonyms

 Futoquinol Biological Activity

Description Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities[1].
Related Catalog
In Vitro Futoquinol potently inhibits NO production with an IC50 value of 16.8 μM in LPS-activated BV-2 cells, a microglia cell line[1].
References

[1]. Ki Hyun Kim, et al. Neolignans from Piper kadsura and their anti-neuroinflammatory activity. Bioorg Med Chem Lett. 2010 Jan 1;20(1):409-12.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 515.0±50.0 °C at 760 mmHg
Molecular Formula C21H22O5
Molecular Weight 354.396
Flash Point 225.5±30.2 °C
Exact Mass 354.146729
PSA 53.99000
LogP 4.82
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.582

 Safety Information

Hazard Codes Xi

 Synonyms

2-Allyl-4-[(1E)-1-(1,3-benzodioxol-5-yl)-1-propen-2-yl]-4,5-dimethoxy-2,5-cyclohexadien-1-one
2-Allyl-4-[(E)-2-(1,3-benzodioxol-5-yl)-1-methylethenyl]-4,5-dimethoxy-2,5-cyclohexadien-1-one
(E)-2-Allyl-4-(2-(1,3-benzodioxol-5-yl)-1-methylvinyl)-4,5-dimethoxy-2,5-cyclohexadien-1-one
2,5-Cyclohexadien-1-one, 4-[(E)-2-(1,3-benzodioxol-5-yl)-1-methylethenyl]-4,5-dimethoxy-2-(2-propen-1-yl)-
Futoquinol