INDOMETHACIN ESTER, N-HEPTYL-

Modify Date: 2024-02-02 17:50:38

INDOMETHACIN ESTER, N-HEPTYL- Structure
INDOMETHACIN ESTER, N-HEPTYL- structure
Common Name INDOMETHACIN ESTER, N-HEPTYL-
CAS Number 282728-47-6 Molecular Weight 455.97
Density 1.2±0.1 g/cm3 Boiling Point 533.6±50.0 °C at 760 mmHg
Molecular Formula C26H30ClNO4 Melting Point N/A
MSDS N/A Flash Point 276.5±30.1 °C

 Use of INDOMETHACIN ESTER, N-HEPTYL-


Indomethacin heptyl ester is a selective COX-2 inhibitor with IC50 of 0.04 μM, exhibits anti-inflammatory activity[1].

 Names

Name Heptyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acet ate
Synonym More Synonyms

 INDOMETHACIN ESTER, N-HEPTYL- Biological Activity

Description Indomethacin heptyl ester is a selective COX-2 inhibitor with IC50 of 0.04 μM, exhibits anti-inflammatory activity[1].
Related Catalog
References

[1]. A S Kalgutkar, et al. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. J Med Chem. 2000 Jul 27;43(15):2860-70.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 533.6±50.0 °C at 760 mmHg
Molecular Formula C26H30ClNO4
Molecular Weight 455.97
Flash Point 276.5±30.1 °C
Exact Mass 455.186340
PSA 57.53000
LogP 6.75
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.565

 Synonyms

Heptyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, heptyl ester