4-biphenyl-4-yl-thiazol-2-ylamine

Modify Date: 2024-01-14 12:14:40

4-biphenyl-4-yl-thiazol-2-ylamine Structure
4-biphenyl-4-yl-thiazol-2-ylamine structure
Common Name 4-biphenyl-4-yl-thiazol-2-ylamine
CAS Number 2834-79-9 Molecular Weight 252.33400
Density 1.23 g/cm3 Boiling Point 489ºC at 760 mmHg
Molecular Formula C15H12N2S Melting Point 129-132 °C(lit.)
MSDS N/A Flash Point 249.5ºC

 Names

Name 4-(4-phenylphenyl)-1,3-thiazol-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.23 g/cm3
Boiling Point 489ºC at 760 mmHg
Melting Point 129-132 °C(lit.)
Molecular Formula C15H12N2S
Molecular Weight 252.33400
Flash Point 249.5ºC
Exact Mass 252.07200
PSA 67.15000
LogP 4.64050
Vapour Pressure 1.04E-09mmHg at 25°C
Index of Refraction 1.665

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ2275000
CHEMICAL NAME :
Thiazole, 2-amino-4-(4-biphenylyl)-
CAS REGISTRY NUMBER :
2834-79-9
BEILSTEIN REFERENCE NO. :
0187642
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H12-N2-S
MOLECULAR WEIGHT :
252.35
WISWESSER LINE NOTATION :
T5N CSJ BZ ER DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,11,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

 Safety Information

Hazard Codes Xi
Risk Phrases 25-41
Safety Phrases 26-39-45
HS Code 2934100090

 Synthetic Route

~86%

4-biphenyl-4-yl-thiazol-2-ylamine Structure

4-biphenyl-4-yl...

CAS#:2834-79-9

Literature: Hanke, Thomas; Dehm, Friederike; Liening, Stefanie; Popella, Sven-Desiderius; MacZewsky, Jonas; Pillong, Max; Kunze, Jens; Weinigel, Christina; Barz, Dagmar; Kaiser, Astrid; Wurglics, Mario; Laemmerhofer, Michael; Schneider, Gisbert; Sautebin, Lidia; Schubert-Zsilavecz, Manfred; Werz, Oliver Journal of Medicinal Chemistry, 2013 , vol. 56, # 22 p. 9031 - 9044

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4-biphenyl-4-yl-thiazol-2-ylamine Structure

4-biphenyl-4-yl...

CAS#:2834-79-9

Literature: King; Hlavacek Journal of the American Chemical Society, 1950 , vol. 72, p. 3722

~%

4-biphenyl-4-yl-thiazol-2-ylamine Structure

4-biphenyl-4-yl...

CAS#:2834-79-9

Literature: Yin, Guodong; Ma, Junrui; Shi, Houqiang; Tao, Qing Heterocycles, 2012 , vol. 85, # 8 p. 1941 - 1948

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

4-Biphenyl-4-ylthiazol-2-ylamine
2-amino-4-(4-biphenyl)thiazole
4-(biphenyl-4-yl)-1,3-thiazol-2-amine
F0777-1464
4-(biphenyl-4-yl)thiazol-2-amine
2-Amino-4-(4-biphenylyl)thiazole
4-([1,1'-biphenyl]-4-yl)thiazol-2-amine
4-Biphenyl-4-yl-thiazol-2-ylamin
4-(1,1'-biphenyl)-4-yl-2-thiazolamine
USAF EK-4373
MFCD00047059
4-(1,1'-biphenyl-4-yl)-1,3-thiazol-2-amine
Thiazole,2-amino-4-(4-biphenylyl)
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