STING modulator-3

Modify Date: 2024-01-02 16:10:46

STING modulator-3 structure	Common Name	STING modulator-3
	CAS Number	2839639-94-8	Molecular Weight	375.39
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇N₉O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of STING modulator-3

STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells[1].

Name	STING modulator-3

Description	STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> STING
In Vitro	STING modulator-3 (AIP01) (10 μM；3 h，24 h) 分别不影响处理 THP-1 细胞 3 h 时，IRF-3 的磷酸化或是处理 24 h 时，对 TNF-β 的诱导[1]。
References	[1]. Gajiwala KS, et al. Imidazole derivatives as STING modulators and their preparation, pharmaceutical compositions and use in the treatment of cancer: World Intellectual Property Organization, WO2022195462. 2022-09-22.

Molecular Formula	C₁₈H₁₇N₉O
Molecular Weight	375.39

STING modulator-3

Use of STING modulator-3

Names

STING modulator-3 Biological Activity

Chemical & Physical Properties