7-Geranyloxy-6-methoxycoumarin

Modify Date: 2025-08-25 16:56:04

7-Geranyloxy-6-methoxycoumarin Structure
7-Geranyloxy-6-methoxycoumarin structure
Common Name 7-Geranyloxy-6-methoxycoumarin
CAS Number 28587-43-1 Molecular Weight 328.402
Density 1.1±0.1 g/cm3 Boiling Point 487.1±45.0 °C at 760 mmHg
Molecular Formula C20H24O4 Melting Point N/A
MSDS N/A Flash Point 213.2±28.8 °C

 Use of 7-Geranyloxy-6-methoxycoumarin


7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia[1].

 Names

Name 7-[(2E)-3,7-dimethylocta-2,6-dienoxy]-6-methoxychromen-2-one
Synonym More Synonyms

 7-Geranyloxy-6-methoxycoumarin Biological Activity

Description 7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia[1].
Related Catalog
References

[1]. Chukaew A, et al. Potential anti-allergic acridone alkaloids from the roots of Atalantia monophylla. Phytochemistry. 2008 Oct;69(14):2616-20.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 487.1±45.0 °C at 760 mmHg
Molecular Formula C20H24O4
Molecular Weight 328.402
Flash Point 213.2±28.8 °C
Exact Mass 328.167450
PSA 48.67000
LogP 5.51
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.542
InChIKey NLNMITFNBJXRRP-XNTDXEJSSA-N
SMILES COc1cc2ccc(=O)oc2cc1OCC=C(C)CCC=C(C)C

 Safety Information

Hazard Codes Xi
HS Code 2932209090

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 7-Geranyloxy-6-methoxycoumarinBioassay

View more

Name: Partial agonist activity at PPARgamma in human BMMSC cells assessed as increase in si...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor gamma
External Id: CHEMBL5229448
Name: Partial agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown orig...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor gamma
External Id: CHEMBL5229446
Name: Partial agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown orig...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor gamma
External Id: CHEMBL5229441
Name: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2353024
Name: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2353252
Name: Cytotoxicity against mouse Melan-a cells assessed as effect on cell viability at <2 u...
Source: ChEMBL
Target: Melan-a
External Id: CHEMBL4154459
Name: Agonist activity at GST-tagged FXR ligand binding domain (unknown origin) at 10 uM La...
Source: ChEMBL
Target: Bile acid receptor
External Id: CHEMBL5229433
Name: Induction of melanogenesis in mouse Melan-a cells assessed as effect on tanning prope...
Source: ChEMBL
Target: Melan-a
External Id: CHEMBL4154460
Name: Agonist activity at GST-tagged LXR-beta ligand binding domain (unknown origin) at 10 ...
Source: ChEMBL
Target: Oxysterols receptor LXR-beta
External Id: CHEMBL5229432
Name: Inhibition of melanogenesis in mouse Melan-a cells assessed as effect on whitening pr...
Source: ChEMBL
Target: Melan-a
External Id: CHEMBL4154461
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 Synonyms

O-geranylscopoletin
6-methoxyaurapten
7-O-Geranyl-esculetin
W1285
7-O-geranylscopoletin
7-Geranyloxy-6-methoxycoumarin
6-methoxy-7-geranyloxycoumarin
7-{[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy}-6-methoxy-2H-chromen-2-one
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