RUNX-IN-2

Modify Date: 2024-01-04 23:40:08

RUNX-IN-2 structure	Common Name	RUNX-IN-2
	CAS Number	2893777-88-1	Molecular Weight	1524.52
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₁H₈₈Cl₂N₂₄O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RUNX-IN-2

RUNX-IN-2 (Compound Conjugate 3) covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. RUNX-IN-2 induces the p53-dependent apoptosis and inhibits cancer cell growth. RUNX-IN-2 inhibits tumor growth in PANC-1 xenograft mice. RUNX-IN-2 has high alkylation efficiency and specificity[1].

Name	RUNX-IN-2

Description	RUNX-IN-2 (Compound Conjugate 3) covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. RUNX-IN-2 induces the p53-dependent apoptosis and inhibits cancer cell growth. RUNX-IN-2 inhibits tumor growth in PANC-1 xenograft mice. RUNX-IN-2 has high alkylation efficiency and specificity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
Target	RUNX[1]
References	[1]. Hirose Y, et al. Anticancer Activities of DNA-Alkylating Pyrrole-Imidazole Polyamide Analogs Targeting RUNX Transcription Factors against p53-Mutated Pancreatic Cancer PANC-1 Cells. J Med Chem. 2023 Sep 14;66(17):12059-12068.

Molecular Formula	C₇₁H₈₈Cl₂N₂₄O₁₁
Molecular Weight	1524.52

RUNX-IN-2

Use of RUNX-IN-2

Names

RUNX-IN-2 Biological Activity

Chemical & Physical Properties