Pyrazine

Modify Date: 2025-08-21 11:16:31

Pyrazine structure	Common Name	Pyrazine
	CAS Number	290-37-9	Molecular Weight	80.088
	Density	1.1±0.1 g/cm3	Boiling Point	118.6±13.0 °C at 760 mmHg
	Molecular Formula	C₄H₄N₂	Melting Point	50-56 °C(lit.)
	MSDS	Chinese USA	Flash Point	55.6±0.0 °C
	Symbol	GHS02, GHS07	Signal Word	Danger

Name	pyrazine
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	118.6±13.0 °C at 760 mmHg
Melting Point	50-56 °C(lit.)
Molecular Formula	C₄H₄N₂
Molecular Weight	80.088
Flash Point	55.6±0.0 °C
Exact Mass	80.037445
PSA	25.78000
LogP	-0.28
Vapour Pressure	19.7±0.2 mmHg at 25°C
Index of Refraction	1.503
InChIKey	KYQCOXFCLRTKLS-UHFFFAOYSA-N
SMILES	c1cnccn1
Storage condition	Flammables area
Stability	Stable. Highly flammable. Incompatible with acids, oxidizing agents.
Water Solubility	SOLUBLE

Pyrazine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ2015000

CHEMICAL NAME :: Pyrazine

CAS REGISTRY NUMBER :: 290-37-9

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C4-H4-N2

MOLECULAR WEIGHT :: 80.10

WISWESSER LINE NOTATION :: T6N DNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2730 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 2500 mg/L

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,581,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5605 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 61 (estimated) No. of Female Employees: 3 (estimated)

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H228-H315-H319-H335
Precautionary Statements	P210-P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi,F
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin . R11:Highly Flammable.
Safety Phrases	S26-S36-S16
RIDADR	UN 1325 4.1/PG 2
WGK Germany	3
RTECS	UQ2015000
Packaging Group	III
Hazard Class	4.1
HS Code	29339990

Precursor 10
CAS#:19847-12-2 Pyrazinecarbonitrile CAS#:110-85-0 Piperazine CAS#:107-15-3 1,2-Ethanediamine CAS#:56-81-5 Glycerol
CAS#:123-32-0 2,5-Dimethylpyrazine CAS#:141-43-5 2-Aminoethanol CAS#:14508-49-7 2-Chloropyrazine CAS#:74-88-4 methyl iodide
CAS#:1151544-30-7 [magnesium(boro... CAS#:57-55-6 Propylene Glycol
DownStream 10
CAS#:108030-81-5 2-(4-Methoxyphe... CAS#:32111-21-0 2-Iodopyrazine CAS#:10199-00-5 2,2′-bipyrazine CAS#:1093418-77-9 2,5-Diiodopyrazine
CAS#:4774-14-5 2,6-Dichloropyrazine CAS#:14508-49-7 2-Chloropyrazine CAS#:19745-07-4 2,5-Dichloropyrazine CAS#:4858-85-9 2,3-Dichloropyrazine
CAS#:3676-97-9 tetramethylbiph... CAS#:101330-13-6 1,4-Bis(dimethy...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

The Inhibition of Maillard Browning by Different Concentrations of Rosmarinic Acid and Epigallocatechin-3-Gallate in Model, Bakery, and Fruit Systems.

J. Food Sci. 80 , C2140-6, (2015)

Rosmarinic acid and Epigallocatechin gallate concentrations were studied as natural inhibitors of Maillard browning in glucose/glycine model systems, and in bakery rolls and applesauce. The concentrat...

Influence of Free Amino Acids, Oligopeptides, and Polypeptides on the Formation of Pyrazines in Maillard Model Systems.

J. Agric. Food Chem. 63 , 5364-72, (2015)

Pyrazines are specific Maillard reaction compounds known to contribute to the unique aroma of many products. Most studies concerning the generation of pyrazines in the Maillard reaction have focused o...

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: qHTS assay to identify small molecule antagonists of the peroxisome proliferator-acti...
Source: 824
Target: N/A
External Id: PPARGV841

Name: qHTS assay to identify small molecule agonists of the TGF-beta/Smad signaling pathway...
Source: 824
Target: N/A
External Id: TGF788

Name: qHTS assay to identify small molecule antagonists of the TGF-beta/Smad signaling path...
Source: 824
Target: N/A
External Id: TGF602

Name: qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell fr...
Source: 824
Target: N/A
External Id: SPEC167MG

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: qHTS assay to identify small molecule agonists of the peroxisome proliferator-activat...
Source: 824
Target: N/A
External Id: PPARDV813

Name: qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free...
Source: 824
Target: N/A
External Id: SPEC167MR

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells
Source: 824
Target: N/A
External Id: SPEC167CG

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Paradiazine

EINECS 206-027-6

Piazine

MFCD00006122

1,4-Diazabenzene

Pyrazine

1,4-Diazine

p-Diazine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Pyrazine
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pyrazine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pyrazine
Price: ￥98.0/25g ￥578.0/500g ￥248.0/100g
Purity: 99.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 290-37-9 Pyrazine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Pyrazine

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Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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Precursor & DownStream

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Articles2

PyrazineBioassay

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