2,6-Dichloropyrazine

Modify Date: 2024-01-02 19:46:23

2,6-Dichloropyrazine Structure
2,6-Dichloropyrazine structure
Common Name 2,6-Dichloropyrazine
CAS Number 4774-14-5 Molecular Weight 148.97
Density 1.5±0.1 g/cm3 Boiling Point 187.5±35.0 °C at 760 mmHg
Molecular Formula C4H2Cl2N2 Melting Point 55-58 °C(lit.)
MSDS Chinese USA Flash Point 83.8±11.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2,6-Dichloropyrazine


2,6-Dichloropyrazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 2,6-Dichloropyrazine
Synonym More Synonyms

 2,6-Dichloropyrazine Biological Activity

Description 2,6-Dichloropyrazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 2,6-Dichloropyrazine 用于制备吡嗪和吡啶类化合物作为 ATR 激酶抑制剂。它还用于合成含氮杂环的氧杂杯芳烃。

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 187.5±35.0 °C at 760 mmHg
Melting Point 55-58 °C(lit.)
Molecular Formula C4H2Cl2N2
Molecular Weight 148.97
Flash Point 83.8±11.5 °C
Exact Mass 147.959503
PSA 25.78000
LogP 1.57
Vapour Pressure 0.9±0.3 mmHg at 25°C
Index of Refraction 1.559

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R20/21/22;R36/37/38
Safety Phrases S26-S37/39-S36/37/39-S22
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

~84%

2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Dickschat, Jeroen S.; Reichenbach, Hans; Wagner-Doebler, Irene; Schulz, Stefan European Journal of Organic Chemistry, 2005 , # 19 p. 4141 - 4153

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2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Am. Cyanamid Co. Patent: US2540476 , 1948 ;

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2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Am. Cyanamid Co. Patent: US2573268 , 1948 ;

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2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Sato, Nobuhiro; Fujii, Megumi Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 5 p. 1177 - 1180

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2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Sato, Nobuhiro Journal of Chemical Research, Miniprint, 1984 , # 10 p. 2860 - 2875

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2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Am. Cyanamid Co. Patent: US2797219 , 1955 ;

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Detail
Literature: Sato, Nobuhiro Journal of Chemical Research, Miniprint, 1984 , # 10 p. 2860 - 2875

~%

Detail
Literature: Am. Cyanamid Co. Patent: US2540476 , 1948 ;

~%

2,6-Dichloropyrazine Structure

2,6-Dichloropyrazine

CAS#:4774-14-5

Literature: Sato, Nobuhiro Journal of Chemical Research, Miniprint, 1984 , # 10 p. 2860 - 2875

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

More Articles
Syntheses and properties of two-dimensional, dicationic nonlinear optical chromophores based on pyrazinyl cores.

J. Org. Chem. 75(24) , 8550-63, (2010)

Six new dicationic 2D nonlinear optical (NLO) chromophores with pyrazinyl-pyridinium electron acceptors have been synthesized by nucleophilic substitutions of 2,6-dichloropyrazine with pyridyl derivat...

Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.

Bioorg. Med. Chem. 21(21) , 6732-41, (2013)

Dicationic 2,6-diphenylpyrazines, aza-analogues and prodrugs were synthesized; evaluated for DNA affinity, activity against Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.) ...

Synthesis of oxacalixarenes incorporating nitrogen heterocycles: evidence for thermodynamic control.

Org. Lett. 8 , 2755, (2006)

[structure: see text] Oxacalix[2]arene[2]hetarenes are formed in a single step by cyclooligomerization of meta-diphenols with meta-dichlorinated azaheterocycles. The high selectivity for cyclic tetram...

 Synonyms

3,5-dichloropyrazine
2,6-dichloropyridazine
Pyrazine,2,6-dichloro
1,6-dichloroypyrazine
Pyrazine, 2,6-dichloro-
2,5-DICHLORO-P-XYLENE
2,6-dichloro-pyrazine
M-Dichloropyrazine
2,6-CHLORO PYRAZINE
2,6-dichloro-pyrazin
2,6-Dichloropyrazine
6-Dichloropyrazine
2,6-Dichlor-pyrazin
EINECS 225-316-8
MFCD00006125