Anticancer agent 99
Modify Date: 2024-04-03 18:33:13
Anticancer agent 99 structure
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Common Name | Anticancer agent 99 | ||
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| CAS Number | 2914922-83-9 | Molecular Weight | 379.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H20F3N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Anticancer agent 99Anticancer agent 99 (compound 2p) has good anticancer activity against HepG2 cells, with an IC50 value of 35.9 μM. Anticancer agent 99 can induce apoptosis and has anti-proliferation effect[1]. |
| Name | Anticancer agent 99 |
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| Description | Anticancer agent 99 (compound 2p) has good anticancer activity against HepG2 cells, with an IC50 value of 35.9 μM. Anticancer agent 99 can induce apoptosis and has anti-proliferation effect[1]. |
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| Related Catalog | |
| In Vitro | Anticancer agent 99 (0-50 μM, 24 h)可直接上调 Bax 表达并诱导 HepG2 细胞系中的 caspase-3 依赖性细胞凋亡，具有抗增殖作用[1]。 Apoptosis Analysis[1] Cell Line: HepG2 cell Concentration: 25, 50 μM Incubation Time: 24 h Result: Increased mRNA transcript levels of pro-apoptotic Bax and Caspase-3 genes. Reduced Akt protein levels in HepG2 cells. Increased FoXO1, TXNIP and p27 protein levels in HepG2 cells. |
| References |
| Molecular Formula | C19H20F3N3O2 |
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| Molecular Weight | 379.38 |