2'-Deoxyadenosine-5'-monophosphate disodium salt

Modify Date: 2024-01-05 00:42:28

2'-Deoxyadenosine-5'-monophosphate disodium salt structure	Common Name	2'-Deoxyadenosine-5'-monophosphate disodium salt
	CAS Number	2922-74-9	Molecular Weight	375.185
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₂N₅Na₂O₆P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-Deoxyadenosine-5'-monophosphate disodium salt

2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1].

Name	2'-Deoxyadenosine-5'-monophosphate disodium salt
Synonym	More Synonyms

Description	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	2′-Deoxyadenosine 5′-monophosphate (dAMP) is incorporated into Caco-2 cells in a time-dependent manner. The uptake of 2′-Deoxyadenosine 5′-monophosphate is increased with a drop in pH, suggesting that 2′-Deoxyadenosine 5′-monophosphate transport activity might be linked to the protons. 2′-Deoxyadenosine 5′-monophosphate uptake by Caco-2 cells is pH- and Na+-dependent[1].
References	[1]. Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14(10):e0223892. [2]. V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27(2):496-502.

Molecular Formula	C₁₀H₁₂N₅Na₂O₆P
Molecular Weight	375.185
Exact Mass	375.032074
PSA	181.31000
LogP	0.62380
Storage condition	−20°C
Water Solubility	H2O: 50 mg/mL, clear, colorless