BV 02
Modify Date: 2024-01-09 17:41:53
BV 02 structure
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Common Name | BV 02 | ||
|---|---|---|---|---|
| CAS Number | 292870-53-2 | Molecular Weight | 377.350 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 593.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C20H15N3O5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 312.9±32.9 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
Use of BV 02BV02 is a potent 4-3-3 PPI (14-3-3 protein–protein interaction) inhibitor. BV02 shows cytotoxicity for hematopoietic cells expressing the IM (imatinib mesylate)-sensitive wild type Bcr-Abl and the IM-resistant T315I mutation. BV02 has the potential for the research of chronic myeloid leukemia[1][2]. |
| Name | 2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxo-5-isoindolinecarboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | BV02 is a potent 4-3-3 PPI (14-3-3 protein–protein interaction) inhibitor. BV02 shows cytotoxicity for hematopoietic cells expressing the IM (imatinib mesylate)-sensitive wild type Bcr-Abl and the IM-resistant T315I mutation. BV02 has the potential for the research of chronic myeloid leukemia[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 593.8±60.0 °C at 760 mmHg |
| Molecular Formula | C20H15N3O5 |
| Molecular Weight | 377.350 |
| Flash Point | 312.9±32.9 °C |
| Exact Mass | 377.101166 |
| LogP | 0.59 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.707 |
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Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interaction.
PLoS ONE 9(5) , e97696, (2014) This study describes the development of aptamers as a therapy against influenza virus infection. Aptamers are oligonucleotides (like ssDNA or RNA) that are capable of binding to a variety of molecular... |
| 2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxo-5-isoindolinecarboxylic acid |
| 1H-Isoindole-5-carboxylic acid, 2-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2,3-dihydro-1,3-dioxo- |
| 2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid |