H-Pro-Gly-NH2 · HCl
Modify Date: 2024-01-09 14:37:00
H-Pro-Gly-NH2 · HCl structure
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Common Name | H-Pro-Gly-NH2 · HCl | ||
|---|---|---|---|---|
| CAS Number | 295350-45-7 | Molecular Weight | 1459.091 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C72H96ClN17O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of H-Pro-Gly-NH2 · HClOzarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer[1]. |
| Name | Ozarelix |
|---|---|
| Synonym | More Synonyms |
| Description | Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Ozarelix (0-20 ng/mL, 72 h) inhibits PC3 and DU145 cell proliferation[1]. Ozarelix (0-20 ng/mL, 72 h) induces apoptosis in PC3 and DU145 cells[1]. Ozarelix (20 ng/mL, 72 h) triggers caspase 8-dependent caspase 3 activation[1]. Cell Proliferation Assay[1] Cell Line: Serum-starved PC3 and DU145 cells Concentration: 0, 5, 10, 20 ng/mL Incubation Time: 0, 24, 48, 72, 96 h Result: Inhibited cell proliferation in a dose and time-dependent manner. Western Blot Analysis[1] Cell Line: PC3 and DU145 cells Concentration: 0, 5, 10, 20 ng/mL Incubation Time: 72 h Result: Increased the levels of p21 and p27 both in PC3 and DU145 cells. Decreased levels of anti-apoptotic proteins such as Bcl2 and Bcl-Xl. Upregulated Erk and p38MAPK activity. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C72H96ClN17O14 |
| Molecular Weight | 1459.091 |
| Exact Mass | 1457.701172 |
| PSA | 486.88000 |
| LogP | 3.42 |
| Index of Refraction | 1.659 |
| Ozarelix |
| N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-N6-(aminocarbonyl)-D-lysyl-L-norleucyl-L-arginyl-L-prolyl-D-alaninamide |
| D 63153 |
| D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-N-(aminocarbonyl)-D-lysyl-L-norleucyl-L-arginyl-L-prolyl- |
| D-63153 |
| N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-N-carbamoyl-D-lysyl-L-norleucyl-L-arginyl-L-prolyl-D-alaninamide |
| UNII-Q1IF8M2YL3 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Ozarelix
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Ozarelix
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: H-Pro-Gly-NH2 · HCl
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Vinnie
- Email: Jamie@api-made.com
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