5'-O-Trt-Zidovudine

Modify Date: 2024-01-10 18:00:19

5'-O-Trt-Zidovudine structure	Common Name	5'-O-Trt-Zidovudine
	CAS Number	29706-84-1	Molecular Weight	509.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₇N₅O₄	Melting Point	103-104 °C(Solv: toluene (108-88-3))
	MSDS	N/A	Flash Point	N/A

Use of 5'-O-Trt-Zidovudine

3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym	More Synonyms

Description	3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Melting Point	103-104 °C(Solv: toluene (108-88-3))
Molecular Formula	C₂₉H₂₇N₅O₄
Molecular Weight	509.56
Exact Mass	509.20600
PSA	123.33000
LogP	4.68516
Storage condition	2-8℃