Meconin-d3

Modify Date: 2024-01-03 18:27:23

Meconin-d3 Structure
Meconin-d3 structure
Common Name Meconin-d3
CAS Number 29809-15-2 Molecular Weight 197.202
Density 1.3±0.1 g/cm3 Boiling Point 404.2±45.0 °C at 760 mmHg
Molecular Formula C10H7D3O4 Melting Point N/A
MSDS N/A Flash Point 185.1±28.8 °C

 Use of Meconin-d3


Meconin-d3 is the deuterium labeled Meconine. Meconine is an endogenous metabolite[1][2].

 Names

Name 6-methoxy-7-(trideuteriomethoxy)-3H-2-benzofuran-1-one
Synonym More Synonyms

 Meconin-d3 Biological Activity

Description Meconin-d3 is the deuterium labeled Meconine. Meconine is an endogenous metabolite[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Jones JT, et al. Detection of codeine, morphine, 6-monoacetylmorphine, and meconin in human umbilical cord tissue: method validation and evidence of in utero heroin exposure. Ther Drug Monit. 2015;37(1):45-52.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 404.2±45.0 °C at 760 mmHg
Molecular Formula C10H7D3O4
Molecular Weight 197.202
Flash Point 185.1±28.8 °C
Exact Mass 197.076736
PSA 44.76000
LogP 0.63
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.548

 Synonyms

Meconin-d3
1(3H)-Isobenzofuranone, 6-methoxy-7-(methyl-d-oxy)-
Meconic Lactone-d3
Opianyl-d3
6-Methoxy-7-[(H)methyloxy]-2-benzofuran-1(3H)-one
6,7-Dimethoxyphthalide-d3