6-Methylflavone
Modify Date: 2025-08-28 11:50:27
6-Methylflavone structure
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Common Name | 6-Methylflavone | ||
|---|---|---|---|---|
| CAS Number | 29976-75-8 | Molecular Weight | 236.26500 | |
| Density | 1.208g/cm3 | Boiling Point | 395.5ºC at 760mmHg | |
| Molecular Formula | C16H12O2 | Melting Point | 119-122 °C (dec.)(lit.) | |
| MSDS | N/A | Flash Point | 183.8ºC | |
Use of 6-Methylflavone6-methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. |
| Name | 6-methyl-2-phenylchromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | 6-methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. |
|---|---|
| Related Catalog | |
| Target |
α1β2γ2L GABAA receptor, α1β2 GABAA receptor[1] |
| In Vitro | 6-methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α1β2γ2L and α1β2 GABAA receptors (P<0.0001) at concentrations from 1 to 100 μM. 6-Methylflavone (60 μM) shifts the GABA dose-response curve to the left (n=4, F=16.38, P=0.0004), decreasing the mean EC50 at α1β2γ2L GABAA receptors by 33±5.4%[1]. |
| References |
| Density | 1.208g/cm3 |
|---|---|
| Boiling Point | 395.5ºC at 760mmHg |
| Melting Point | 119-122 °C (dec.)(lit.) |
| Molecular Formula | C16H12O2 |
| Molecular Weight | 236.26500 |
| Flash Point | 183.8ºC |
| Exact Mass | 236.08400 |
| PSA | 30.21000 |
| LogP | 3.76840 |
| Vapour Pressure | 1.83E-06mmHg at 25°C |
| Index of Refraction | 1.623 |
| InChIKey | NOQJBXPAMJLUSS-UHFFFAOYSA-N |
| SMILES | Cc1ccc2oc(-c3ccccc3)cc(=O)c2c1 |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | 36/37/38 |
| Safety Phrases | S26-S36 |
| WGK Germany | 3 |
| HS Code | 2914399090 |
| HS Code | 2914399090 |
|---|---|
| Summary | 2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
|
|
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
|
|
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
|
|
Name: Ability to inhibit [3H]-Ro- 15-1788 binding to Gamma-aminobutyric acid A receptor alp...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-3
External Id: CHEMBL679569
|
|
Name: qHTS for inhibitors of Vif-A3G interactions: Validation
Source: NCGC
Target: DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens]
External Id: VIFG001
|
|
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
|
|
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
|
|
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
|
|
Name: In vitro affinity against Benzodiazepine receptor binding to rat cortical membranes (...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-3
External Id: CHEMBL651177
|
|
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
|
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| 6-methyl-2-phenyl-4H-1-benzopyran-4-one |
| MFCD00017461 |
| 2-phenyl-6-methylchromone |
| 6-methyl-flavone |
| 6-Methylflavone |