3,5-Dibromo-L-tyrosine
3,5-Dibromo-L-tyrosine structure
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Common Name | 3,5-Dibromo-L-tyrosine | ||
|---|---|---|---|---|
| CAS Number | 300-38-9 | Molecular Weight | 338.981 | |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 416.6±45.0 °C at 760 mmHg | |
| Molecular Formula | C9H9Br2NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 205.7±28.7 °C | |
Use of 3,5-Dibromo-L-tyrosine3,5-Dibromotyrosine is a product of protein oxidation by eosinophil peroxidase[1]. |
Summary: 3,5-dibromo-L-tyrosine (CAS number: 300-38-9) is a chemical with the molecular formula C9H9Br2NO3 and a molecular weight of 338.981. This compound is almost completely soluble in 1mol/L HCl. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3,5-dibromo-L-tyrosine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 3,5-Dibromotyrosine is a product of protein oxidation by eosinophil peroxidase[1]. |
|---|---|
| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 416.6±45.0 °C at 760 mmHg |
| Molecular Formula | C9H9Br2NO3 |
| Molecular Weight | 338.981 |
| Flash Point | 205.7±28.7 °C |
| Exact Mass | 336.894897 |
| PSA | 83.55000 |
| LogP | 2.31 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.669 |
| InChIKey | COESHZUDRKCEPA-ZETCQYMHSA-N |
| SMILES | NC(Cc1cc(Br)c(O)c(Br)c1)C(=O)O |
| Storage condition | Store at RT. |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Safety Phrases | S22-S24/25 |
|---|---|
| WGK Germany | 3 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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3,5-Dibromo-L-t... CAS#:300-38-9 |
| Literature: Gao, Hongfeng; Kelly, Michelle; Hamann, Mark T. Tetrahedron, 1999 , vol. 55, # 32 p. 9717 - 9726 |
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~19%
3,5-Dibromo-L-t... CAS#:300-38-9
Learn More
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| Literature: Chemical and Pharmaceutical Bulletin, , vol. 54, # 12 p. 1715 - 1719 |
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~%
3,5-Dibromo-L-t... CAS#:300-38-9 |
| Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 144, p. 277,280 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 5 | |
CAS#:105189-44-4
CAS#:17194-82-0
CAS#:58960-71-7
CAS#:556-02-5
CAS#:537-24-6This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Biochemical assay for compounds that inhibit RGS4 stimulation of Galpha1 nucleotide h...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 [Rattus norvegicus]
External Id: JHICC_RGS4_Inh_SSGAP
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: NCATS Kinetic Aqueous Solubility Profiling
Source: NCGC
Target: N/A
External Id: ADME-solubility1
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Primary cell-based high-throughput screening for identification of compounds that all...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_AlloAgonist_Primary
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Name: Primary cell-based high-throughput screening for identification of compounds that ant...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_Antagonist_Primary
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Second counter screen for identification of compounds that inhibit regulator of G-pro...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Inh_Counter2
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Name: uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent a...
Source: Burnham Center for Chemical Genomics
Target: TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Saccharomyces cerevisiae S288c]
External Id: SBCCG-A413-tim10-1-Primary-Antagonist-Assay
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Name: NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling
Source: NCGC
Target: N/A
External Id: ADME-PAMPA1
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (2S)-2-amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid |
| Dibromotirina |
| 3,5-Dibromo-L-tyrosine |
| H-TYR(3,5-BR 2)-OH 2H2O |
| 3,5-Dibromo-L-tyrosi |
| Biotiren |
| 5,5'-Dibromo-2,2'-dihydroxybenzil |
| β-(3,5-Dibromo-4-hydroxyphenyl)alanine |
| EINECS 206-091-5 |
| MFCD08271759 |
| H-PHE(3,5-BR2,4-OH)-OH DIHYDRATE |
| L-(3,5-DIBROMO)TYROSINE DIHYDRATE |
| Dibromotyrosine |
| L-Tyr(3',5'-Br2) |
| L-3,5-Dibromotyrosine |
| b-(3,5-Dibromo-4-hydroxyphenyl)alanine |
| 3,5-Dibromotyrosine |
| 3,5-Dibrom-L-tyrosin |
| L-4-hydroxy-3,5-dibromo-phenylalanine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of 3,5-dibromo-L-tyrosine? |
| A: The English name of 3,5-dibromo-L-tyrosine is 3,5-dibromo-L-tyrosine. |
| Q: What is the boiling point of 3,5-dibromo-L-tyrosine? |
| A: Boiling point of 3,5-dibromo-L-tyrosine is 416.6±45.0 °C at 760 mmHg. |
| Q: What are the uses of 3,5-dibromo-L-tyrosine? |
| A: Main uses of 3,5-dibromo-L-tyrosine: 3,5-Dibromotyrosine is a product of protein oxidation by eosinophil peroxidase[1]. |
| Q: What are the downstream products of 3,5-dibromo-L-tyrosine? |
| A: Related downstream products(CAS) of 3,5-dibromo-L-tyrosine: 105189-44-4;17194-82-0;58960-71-7;556-02-5;537-24-6. |
| Q: What is the InChIKey of 3,5-dibromo-L-tyrosine? |
| A: InChIKey of 3,5-dibromo-L-tyrosine is COESHZUDRKCEPA-ZETCQYMHSA-N. |
| Q: What is the CAS number of 3,5-dibromo-L-tyrosine? |
| A: CAS number of 3,5-dibromo-L-tyrosine is 300-38-9. |
| Q: What is the molecular formula of 3,5-dibromo-L-tyrosine? |
| A: Molecular formula of 3,5-dibromo-L-tyrosine is C9H9Br2NO3. |
| Q: What are the upstream materials of 3,5-dibromo-L-tyrosine? |
| A: Related upstream materials(CAS) of 3,5-dibromo-L-tyrosine: 60-18-4;7726-95-6;64-19-7. |
| Q: What is the LogP of 3,5-dibromo-L-tyrosine? |
| A: LogP of 3,5-dibromo-L-tyrosine is 2.31. |
| Q: What is the safety information for 3,5-dibromo-L-tyrosine? |
| A: Safety information for 3,5-dibromo-L-tyrosine: S22-S24/25. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |