3,5-Dibromo-L-tyrosine

Modify Date: 2025-08-25 14:52:11

3,5-Dibromo-L-tyrosine Structure
3,5-Dibromo-L-tyrosine structure
Common Name 3,5-Dibromo-L-tyrosine
CAS Number 300-38-9 Molecular Weight 338.981
Density 2.0±0.1 g/cm3 Boiling Point 416.6±45.0 °C at 760 mmHg
Molecular Formula C9H9Br2NO3 Melting Point N/A
MSDS N/A Flash Point 205.7±28.7 °C

 Use of 3,5-Dibromo-L-tyrosine


3,5-Dibromotyrosine is a product of protein oxidation by eosinophil peroxidase[1].

 Names

Name 3,5-dibromo-L-tyrosine
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 416.6±45.0 °C at 760 mmHg
Molecular Formula C9H9Br2NO3
Molecular Weight 338.981
Flash Point 205.7±28.7 °C
Exact Mass 336.894897
PSA 83.55000
LogP 2.31
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.669
InChIKey COESHZUDRKCEPA-ZETCQYMHSA-N
SMILES NC(Cc1cc(Br)c(O)c(Br)c1)C(=O)O
Storage condition Store at RT.

 Safety Information

Safety Phrases S22-S24/25
WGK Germany 3

 Synthetic Route

~94%

3,5-Dibromo-L-tyrosine Structure

3,5-Dibromo-L-t...

CAS#:300-38-9

Literature: Gao, Hongfeng; Kelly, Michelle; Hamann, Mark T. Tetrahedron, 1999 , vol. 55, # 32 p. 9717 - 9726

~19%

3,5-Dibromo-L-tyrosine Structure

3,5-Dibromo-L-t...

CAS#:300-38-9

Literature: Chemical and Pharmaceutical Bulletin, , vol. 54, # 12 p. 1715 - 1719

~%

3,5-Dibromo-L-tyrosine Structure

3,5-Dibromo-L-t...

CAS#:300-38-9

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 144, p. 277,280

 3,5-Dibromo-L-tyrosineBioassay

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Name: Biochemical assay for compounds that inhibit RGS4 stimulation of Galpha1 nucleotide h...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 [Rattus norvegicus]
External Id: JHICC_RGS4_Inh_SSGAP
Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: NCATS Kinetic Aqueous Solubility Profiling
Source: NCGC
Target: N/A
External Id: ADME-solubility1
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Primary cell-based high-throughput screening for identification of compounds that all...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_AlloAgonist_Primary
Name: Primary cell-based high-throughput screening for identification of compounds that ant...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_Antagonist_Primary
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Second counter screen for identification of compounds that inhibit regulator of G-pro...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Inh_Counter2
Name: uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent a...
Source: Burnham Center for Chemical Genomics
Target: TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Saccharomyces cerevisiae S288c]
External Id: SBCCG-A413-tim10-1-Primary-Antagonist-Assay
Name: NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling
Source: NCGC
Target: N/A
External Id: ADME-PAMPA1
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 Synonyms

(2S)-2-amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid
Dibromotirina
3,5-Dibromo-L-tyrosine
H-TYR(3,5-BR 2)-OH 2H2O
3,5-Dibromo-L-tyrosi
Biotiren
5,5'-Dibromo-2,2'-dihydroxybenzil
β-(3,5-Dibromo-4-hydroxyphenyl)alanine
EINECS 206-091-5
MFCD08271759
H-PHE(3,5-BR2,4-OH)-OH DIHYDRATE
L-(3,5-DIBROMO)TYROSINE DIHYDRATE
Dibromotyrosine
L-Tyr(3',5'-Br2)
L-3,5-Dibromotyrosine
b-(3,5-Dibromo-4-hydroxyphenyl)alanine
3,5-Dibromotyrosine
3,5-Dibrom-L-tyrosin
L-4-hydroxy-3,5-dibromo-phenylalanine
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