Bronidox

Modify Date: 2024-01-02 12:37:42

Bronidox Structure
Bronidox structure
 Common Name Bronidox
CAS Number 30007-47-7 Molecular Weight 211.999
Density 1.8±0.1 g/cm3 Boiling Point 280.8±40.0 °C at 760 mmHg
Molecular Formula C4H6BrNO4 Melting Point 60°C
MSDS Chinese USA Flash Point 123.6±27.3 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Bronidox


5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol[1].

 Names

Name 5-Bromo-5-nitro-1,3-dioxane
Synonym More Synonyms

 Bronidox Biological Activity

Description 5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol[1].
Related Catalog
References

[1]. M Ghannoum, et al. Mode of Action of the Antimicrobial Compound 5-bromo-5-nitro-1,3-dioxane (Bronidox). Folia Microbiol (Praha). 1986;31(1):19-31.

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 280.8±40.0 °C at 760 mmHg
Melting Point 60°C
Molecular Formula C4H6BrNO4
Molecular Weight 211.999
Flash Point 123.6±27.3 °C
Exact Mass 210.948013
PSA 64.28000
LogP 0.95
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.533

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JG9650000
CHEMICAL NAME :
m-Dioxane, 5-bromo-5-nitro-
CAS REGISTRY NUMBER :
30007-47-7
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C4-H6-Br-N-O4
MOLECULAR WEIGHT :
212.02
WISWESSER LINE NOTATION :
T6O COTJ EE ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
REFERENCE :
FSASAX Fette, Seifen, Anstrichmittel. (Industrieverlag von Hernhaussen KG, Postfach 100252, D-7022 Leinfelden-Echterdingen 1, Fed. Rep. Ger.) V.55- 1953- Volume(issue)/page/year: 78,269,1976
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
REFERENCE :
FSASAX Fette, Seifen, Anstrichmittel. (Industrieverlag von Hernhaussen KG, Postfach 100252, D-7022 Leinfelden-Echterdingen 1, Fed. Rep. Ger.) V.55- 1953- Volume(issue)/page/year: 78,269,1976 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
455 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
FSASAX Fette, Seifen, Anstrichmittel. (Industrieverlag von Hernhaussen KG, Postfach 100252, D-7022 Leinfelden-Echterdingen 1, Fed. Rep. Ger.) V.55- 1953- Volume(issue)/page/year: 78,269,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
31 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
FSASAX Fette, Seifen, Anstrichmittel. (Industrieverlag von Hernhaussen KG, Postfach 100252, D-7022 Leinfelden-Echterdingen 1, Fed. Rep. Ger.) V.55- 1953- Volume(issue)/page/year: 78,269,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
590 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
FSASAX Fette, Seifen, Anstrichmittel. (Industrieverlag von Hernhaussen KG, Postfach 100252, D-7022 Leinfelden-Echterdingen 1, Fed. Rep. Ger.) V.55- 1953- Volume(issue)/page/year: 78,269,1976
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
FSASAX Fette, Seifen, Anstrichmittel. (Industrieverlag von Hernhaussen KG, Postfach 100252, D-7022 Leinfelden-Echterdingen 1, Fed. Rep. Ger.) V.55- 1953- Volume(issue)/page/year: 78,269,1976

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R38
Safety Phrases S36
RIDADR 1759
WGK Germany 3
RTECS JG9650000
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Mode of action of the antimicrobial compound 5-bromo-5-nitro-1,3-dioxane (bronidox).

Folia Microbiol. (Praha) 31 , 19-31, (1986)

The mode of action of the antimicrobial agent, 5-bromo-5-nitro-1,3-dioxane (bronidox), was studied in detail for gram-positive and gram-negative bacteria, yeast and fungi. The studies included MIC tes...

 Synonyms

EINECS 250-001-7
5-bromo-5-nitro-1,3-dioxolane
5-Bromo-5-nitro-m-dioxane
5-bromo-5-nitro-1,3-dioxan
5-Bromo-5-nitro-1,3-dioxane
1,3-Dioxane, 5-bromo-5-nitro-
m-Dioxane, 5-bromo-5-nitro-
MFCD00101855
m-DIOXANE,5-BROMO-5-NITRO
1,3-Dioxane,5-bromo-5-nitro
Bronidox
5-Bromo-5-nitro-1.3-dioxane
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Chemsrc provides Bronidox(CAS#:30007-47-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Bronidox are included as well.>> amp version: Bronidox

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