TG003

Modify Date: 2024-01-05 20:06:47

TG003 structure	Common Name	TG003
	CAS Number	300801-52-9	Molecular Weight	237.318
	Density	1.2±0.1 g/cm3	Boiling Point	353.6±42.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₁₅NO₂S	Melting Point	132-132.5ºC
	MSDS	Chinese USA	Flash Point	167.6±27.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of TG003

TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC.

Name	tg003
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	353.6±42.0 °C at 760 mmHg
Melting Point	132-132.5ºC
Molecular Formula	C₁₂H₁₅NO₂S
Molecular Weight	237.318
Flash Point	167.6±27.9 °C
Exact Mass	237.082352
PSA	51.63000
LogP	1.82
Appearance of Characters	solid \| pale yellow
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.635
Storage condition	2-8°C
Water Solubility	DMSO: 33 mg/mL

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3

Establishment of a monitoring system to detect inhibition of mRNA processing.

Biosci. Biotechnol. Biochem. 76(6) , 1248-51, (2012)

A number of proteins complete mRNA processing in the nucleus, thus, inhibitor of mRNA processing is worth finding to analyze the mechanism of mRNA maturation in detail. Here, we established a monitori...

(2Z)-3-Ethyl-5-methoxy-2-(methoxymethylene)-2,3-dihydro-1,3-benzothiazole

(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one

Benzothiazole, 3-ethyl-2,3-dihydro-5-methoxy-2-(methoxymethylene)-, (2Z)-

MFCD00624584