- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: TG003
- Price: ￥3998.0/25mg ￥1058.0/5mg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: TG003
- Price: $350.0/100mg $700.0/250mg $1400.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
300801-52-9
300801-52-9 structure
- Name: TG003
- Chemical Name: tg003
- CAS Number: 300801-52-9
- Molecular Formula: C12H15NO2S
- Molecular Weight: 237.318
- Catalog: Biochemical Inhibitor Cell Cycle CDK inhibitor
- Create Date: 2018-12-29 09:23:47
- Modify Date: 2024-01-05 20:06:47
-
TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC.
| Name | tg003 |
|---|---|
| Synonyms |
(2Z)-3-Ethyl-5-methoxy-2-(methoxymethylene)-2,3-dihydro-1,3-benzothiazole
(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one Benzothiazole, 3-ethyl-2,3-dihydro-5-methoxy-2-(methoxymethylene)-, (2Z)- MFCD00624584 |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 353.6±42.0 °C at 760 mmHg |
| Melting Point | 132-132.5ºC |
| Molecular Formula | C12H15NO2S |
| Molecular Weight | 237.318 |
| Flash Point | 167.6±27.9 °C |
| Exact Mass | 237.082352 |
| PSA | 51.63000 |
| LogP | 1.82 |
| Appearance | solid | pale yellow |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.635 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: 33 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |