Dc-s239
Modify Date: 2025-08-27 19:59:19
Dc-s239 structure
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Common Name | Dc-s239 | ||
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| CAS Number | 303141-21-1 | Molecular Weight | 349.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H15N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Dc-s239DC-S239 is a selective histone methyltransferase SET7 inhibitor with an IC50 value of 4.59 μM. DC-S239 also displays selectivity for DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a. DC-S239 has anticancer activity[1]. |
| Name | DC-S239 |
|---|
| Description | DC-S239 is a selective histone methyltransferase SET7 inhibitor with an IC50 value of 4.59 μM. DC-S239 also displays selectivity for DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a. DC-S239 has anticancer activity[1]. |
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| Related Catalog | |
| Target |
IC50: 4.59 μM (SET7)[1] |
| In Vitro | DC-S239 inhibits DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a by less than 45%, while it inhibits SET7 by 90% at concentrations of 100 μM[1]. DC-S239 (0-100 μM, 120 h) can inhibit the proliferation of MCF7, HL60 and MV4-11 cells in a dose-dependent manner but no significant effect on the activity of HCT116 and DHL4 cells[1]. Cell Viability Assay[1] Cell Line: MCF7, HL60, DHL4, MV4-11 and HCT116 cell lines Concentration: 0-100 μM Incubation Time: 120 h Result: Inhibited MCF7 and HL60 with the IC50 values of 10.93 μM and 16.43 μM, respectively. |
| References |
| Molecular Formula | C15H15N3O5S |
|---|---|
| Molecular Weight | 349.36 |