Kynuramine Dihydrobromide

Modify Date: 2026-07-01 11:16:13

Kynuramine Dihydrobromide Structure
Kynuramine Dihydrobromide structure
Common Name Kynuramine Dihydrobromide
CAS Number 304-47-2 Molecular Weight 326.02800
Density N/A Boiling Point 367.3ºC at 760mmHg
Molecular Formula C9H14Br2N2O Melting Point N/A
MSDS Chinese USA Flash Point 175.9ºC

 Use of Kynuramine Dihydrobromide


Kynuramine (dihydrobromide), an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase[1][2].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Kynuramine dihydrobromide
Synonym More Synonyms

 Kynuramine Dihydrobromide Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Kynuramine (dihydrobromide), an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase[1][2].
Related Catalog
In Vitro Kynuramine (dihydrobromide) 在体外抑制突触前和突触后 α-肾上腺素受体[2]。 Kynuramine 已被证明是狗脑动脉血清素受体的部分激动剂[2]。 Kynuramine (20 μg/mL) 经常导致回肠轻微收缩,但未能改变胆碱能刺激的抽搐反应[2]。
In Vivo Kynuramine (dihydrobromide) (0.064、0.32、1.6 或 8 μg;脑室内;单剂量) 促进雌激素激发的去卵巢大鼠前凸行为[3]。 Kynuramine (1.25、2.5 和 5.0 mg/kg;静脉注射;单剂量) 可增加大鼠的心率和血压[4]。 Animal Model: Female rats[3]. Dosage: 0.064-8 μg. Administration: Intraventricular injection; single does. Result: Produced facilitation of lordosis behavior. Animal Model: Male rats (about 200g)[4]. Dosage: 1.25-5.0 mg/kg. Administration: Intravenous injection; single does. Result: Promoted heart rate and blood pressure.
References

[1]. J B Massey, et al. Kynuramine, a fluorescent substrate and probe of plasma amine oxidase. J Biol Chem. 1977 Nov 25;252(22):8081-4.  

[2]. T D Johnson, An alpha-adrenoceptor inhibitory action of kynuramine. Eur J Pharmacol. 1981 Jul 10;72(4):351-6.  

[3]. S D Mendelson, et al. Intraventricular administration of l-kynurenine and kynuramine facilitates lordosis in the female rat. Eur J Pharmacol. 1987 Oct 27;142(3):447-51.  

[4]. T D Johnson, et al. Blood pressure and heart rate effects of kynuramine in pithed rats. Eur J Pharmacol. 1983 Feb 18;87(2-3):323-6.  

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Boiling Point 367.3ºC at 760mmHg
Molecular Formula C9H14Br2N2O
Molecular Weight 326.02800
Flash Point 175.9ºC
Exact Mass 323.94700
PSA 69.11000
LogP 3.99800
InChIKey KNLPLQJBAIXOQE-UHFFFAOYSA-N
SMILES Br.Br.NCCC(=O)c1ccccc1N
Storage condition 20°C

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles4

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

3-(2-Aminophenyl)-3-oxopropanamine
3-amino-1-(2-aminophenyl)propan-1-one,hydrobromide

 Kynuramine Dihydrobromide | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the boiling point of Kynuramine dihydrobromide?
A: Boiling point of Kynuramine dihydrobromide is 367.3ºC at 760mmHg.
Q: What is the LogP of Kynuramine dihydrobromide?
A: LogP of Kynuramine dihydrobromide is 3.99800.
Q: What English synonyms does Kynuramine dihydrobromide have?
A: English synonyms of Kynuramine dihydrobromide: 3-(2-Aminophenyl)-3-oxopropanamine, 3-amino-1-(2-aminophenyl)propan-1-one,hydrobromide.
Q: What is the molecular formula of Kynuramine dihydrobromide?
A: Molecular formula of Kynuramine dihydrobromide is C9H14Br2N2O.
Q: What is the English name of Kynuramine dihydrobromide?
A: The English name of Kynuramine dihydrobromide is Kynuramine dihydrobromide.
Q: What is the CAS number of Kynuramine dihydrobromide?
A: CAS number of Kynuramine dihydrobromide is 304-47-2.
Q: What is the polar surface area (PSA) of Kynuramine dihydrobromide?
A: Polar surface area (PSA) of Kynuramine dihydrobromide is 69.11000.
Q: What is the molecular weight of Kynuramine dihydrobromide?
A: Molecular weight of Kynuramine dihydrobromide is 326.02800.
Q: What is the InChIKey of Kynuramine dihydrobromide?
A: InChIKey of Kynuramine dihydrobromide is KNLPLQJBAIXOQE-UHFFFAOYSA-N.
Q: What are the uses of Kynuramine dihydrobromide?
A: Main uses of Kynuramine dihydrobromide: Kynuramine (dihydrobromide), an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase[1][2].

 Kynuramine Dihydrobromidefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
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