BTYNB
Modify Date: 2024-01-08 10:43:53
BTYNB structure
|
Common Name | BTYNB | ||
|---|---|---|---|---|
| CAS Number | 304456-62-0 | Molecular Weight | 309.182 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 495.9±40.0 °C at 760 mmHg | |
| Molecular Formula | C12H9BrN2OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 253.7±27.3 °C | |
Use of BTYNBBTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM; has no effect on binding of PR to flPRE; destabilizes c-Myc mRNA, downregulates β-TrCP1 mRNA and reduces activation of NF-κB; also decreases oncogenic translation regulator eEF2 mRNA levels in cancer cells; potently inhibits proliferation of IMP1-containing ovarian cancer and melanoma cells with no effect in IMP1-negative cells. |
| Name | 2-{(E)-[(5-Bromo-2-thienyl)methylene]amino}benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM; has no effect on binding of PR to flPRE; destabilizes c-Myc mRNA, downregulates β-TrCP1 mRNA and reduces activation of NF-κB; also decreases oncogenic translation regulator eEF2 mRNA levels in cancer cells; potently inhibits proliferation of IMP1-containing ovarian cancer and melanoma cells with no effect in IMP1-negative cells. |
|---|---|
| References | References 1. Mahapatra L, et al. Transl Oncol. 2017 Oct;10(5):818-827. View Related Products by Target c-Myc |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 495.9±40.0 °C at 760 mmHg |
| Molecular Formula | C12H9BrN2OS |
| Molecular Weight | 309.182 |
| Flash Point | 253.7±27.3 °C |
| Exact Mass | 307.961884 |
| LogP | 2.88 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.685 |
| Hazard Codes | Xi |
|---|
| Benzamide, 2-[[(1E)-(5-bromo-2-thienyl)methylene]amino]- |
| 2-{(E)-[(5-Bromo-2-thienyl)methylene]amino}benzamide |
| 2-{[(E)-(5-bromothiophen-2-yl)methylidene]amino}benzamide |
| MFCD00977636 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: BTYNB
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: BTYNB
- Price: $550.0/100mg $850.0/250mg $1800.0/1g $150.0/10ml
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: BTYNB
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-{[(5-bromo-2-thienyl)methylene]amino}benzamide
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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