Mca-Ala-Pro-Lys(Dnp)-OH

Modify Date: 2024-01-16 18:25:40

Mca-Ala-Pro-Lys(Dnp)-OH Structure
Mca-Ala-Pro-Lys(Dnp)-OH structure
Common Name Mca-Ala-Pro-Lys(Dnp)-OH
CAS Number 305336-82-7 Molecular Weight 638.625
Density 1.4±0.1 g/cm3 Boiling Point 989.0±65.0 °C at 760 mmHg
Molecular Formula C30H34N6O10 Melting Point N/A
MSDS N/A Flash Point 551.9±34.3 °C

 Use of Mca-Ala-Pro-Lys(Dnp)-OH


Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung[1][2].

 Names

Name Mca-APK(Dnp)
Synonym More Synonyms

 Mca-Ala-Pro-Lys(Dnp)-OH Biological Activity

Description Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung[1][2].
Related Catalog
In Vitro The activity of ACE2 enzyme detected by: the fluorescent peptide substrate Mca-AlaPro-Lys (Dnp)-OH is hydrolyzed by ACE2 and its product is detected by the active fluorescence resonance energy transfer method[3].
References

[1]. Liu J, Ji H, et al. Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent. Biol Sex Differ. 2010;1(1):6. Published 2010 Nov 5.

[2]. Liang Y, et al. Urinary angiotensin converting enzyme 2 increases in patients with type 2 diabetic mellitus. Kidney Blood Press Res. 2015;40(2):101-110.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 989.0±65.0 °C at 760 mmHg
Molecular Formula C30H34N6O10
Molecular Weight 638.625
Flash Point 551.9±34.3 °C
Exact Mass 638.233643
LogP 3.94
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.658

 Synonyms

N-(4-Methyl-2-oxo-2H-chromen-7-yl)-L-alanyl-L-prolyl-N-(2,4-dinitrophenyl)-L-lysine
L-Lysine, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alanyl-L-prolyl-N-(2,4-dinitrophenyl)-
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