Perfluorodecalin

Modify Date: 2024-01-08 01:18:28

Perfluorodecalin Structure
Perfluorodecalin structure
Common Name Perfluorodecalin
CAS Number 306-94-5 Molecular Weight 462.078
Density 1.8±0.1 g/cm3 Boiling Point 143.1±40.0 °C at 760 mmHg
Molecular Formula C10F18 Melting Point -10ºC
MSDS Chinese USA Flash Point 46.4±19.1 °C

 Use of Perfluorodecalin


Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2].

 Names

Name perfluorodecalin
Synonym More Synonyms

 Perfluorodecalin Biological Activity

Description Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2].
Related Catalog
References

[1]. Orzalesi N, et al. Experimental short-term tolerance to perfluorodecalin in the rabbit eye: a histopathological study. Curr Eye Res. 1998;17(8):828-835.

[2]. Bourke RD, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1994;118(3):403-404.

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 143.1±40.0 °C at 760 mmHg
Melting Point -10ºC
Molecular Formula C10F18
Molecular Weight 462.078
Flash Point 46.4±19.1 °C
Exact Mass 461.971252
LogP 6.03
Vapour density 17.5 (vs air)
Vapour Pressure 6.8±0.3 mmHg at 25°C
Index of Refraction 1.296
Water Solubility Insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ3175000
CHEMICAL NAME :
Naphthalene, decahydrooctadecafluoro-
CAS REGISTRY NUMBER :
306-94-5
BEILSTEIN REFERENCE NO. :
2067113
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-F18
MOLECULAR WEIGHT :
462.10
WISWESSER LINE NOTATION :
L66TJ AF BF BF CF CF DF DF EF EF FF GF GF HF HF IF IF JF JF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>100 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MayGF# Personal Communication from Dr. G.F. May, BNFL Fluorochemicals Ltd., Bldg. 619, Springfields, Salwick, Preston, Lancashire PR4 OXJ. UK, Aug. 25, 1995. Volume(issue)/page/year: 25AUG1995
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>8647 ppm/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB81-156911
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PGPKA8 Problemy Gematologii i Perelivaniia Krovi. Problems of Hematology and Blood Transfusion. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1956- Volume(issue)/page/year: 27(10),8,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 90,1513,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4449 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R10
Safety Phrases S24/25-S41
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS QJ3175000
Packaging Group III
Hazard Class 3.2
HS Code 2903999090

 Customs

HS Code 2903999090
Summary 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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 Synonyms

OCTADECAFLUORODECALIN
perflunafene
perfluorodecahydronaphthalene
F-DC
Naphthalene, 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecahydro-
perfluorodecahydronaphthalin
Perfluorodecalin
pfd
Octadecafluorodecaline
PP 5
EINECS 206-192-4
Perfluoro(decahydronaphthalene)
Octadecafluorodecahydronaphthalene
1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecalin
MFCD00010626
perfluorodecaline
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