L-Tyrosine-d2-1

Modify Date: 2024-01-10 09:51:21

L-Tyrosine-d2-1 Structure
L-Tyrosine-d2-1 structure
Common Name L-Tyrosine-d2-1
CAS Number 30811-19-9 Molecular Weight 183.201
Density 1.3±0.1 g/cm3 Boiling Point 385.2±32.0 °C at 760 mmHg
Molecular Formula C9H9D2NO3 Melting Point >300ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 186.7±25.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of L-Tyrosine-d2-1


L-Tyrosine-d2-1 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

 Names

Name (2S)-2-amino-3-(3,5-dideuterio-4-hydroxyphenyl)propanoic acid
Synonym More Synonyms

 L-Tyrosine-d2-1 Biological Activity

Description L-Tyrosine-d2-1 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 385.2±32.0 °C at 760 mmHg
Melting Point >300ºC (dec.)(lit.)
Molecular Formula C9H9D2NO3
Molecular Weight 183.201
Flash Point 186.7±25.1 °C
Exact Mass 183.086441
PSA 83.55000
LogP 0.38
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.614
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26;S36
RIDADR NONH for all modes of transport

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

<3',5'-2H2>-L-tyrosine
3,5-d2-tyrosine
L-4-Hydroxyphenyl-3,5-d2-alanine
L-Tyrosine-3,5-d
L-<3,5-D2>-tyrosine
MFCD00144699
L-(3,5-H)Tyrosine