4-Chloro-5-sulfamoylanthranilic Acid

Modify Date: 2024-01-04 07:14:20

4-Chloro-5-sulfamoylanthranilic Acid Structure
4-Chloro-5-sulfamoylanthranilic Acid structure
Common Name 4-Chloro-5-sulfamoylanthranilic Acid
CAS Number 3086-91-7 Molecular Weight 250.65900
Density 1.726g/cm3 Boiling Point 549.2ºC at 760mmHg
Molecular Formula C7H7ClN2O4S Melting Point 267°C (dec.) (lit.)
MSDS N/A Flash Point 286ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-amino-4-chloro-5-sulfamoylbenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.726g/cm3
Boiling Point 549.2ºC at 760mmHg
Melting Point 267°C (dec.) (lit.)
Molecular Formula C7H7ClN2O4S
Molecular Weight 250.65900
Flash Point 286ºC
Exact Mass 249.98200
PSA 131.86000
LogP 2.63010
Index of Refraction 1.665

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
Hazard Codes N
RIDADR NONH for all modes of transport
HS Code 2935009090

 Synthetic Route

~51%

4-Chloro-5-sulfamoylanthranilic Acid Structure

4-Chloro-5-sulf...

CAS#:3086-91-7

Literature: NITROMED, INC. Patent: WO2006/55542 A2, 2006 ; Location in patent: Page/Page column 69-70 ; WO 2006/055542 A2

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4-Chloro-5-sulfamoylanthranilic Acid Structure

4-Chloro-5-sulf...

CAS#:3086-91-7

Literature: Journal of the American Chemical Society, , vol. 81, p. 5508 Journal of the American Chemical Society, , vol. 82, p. 2731,2733,2734 US2952680 , ; US2910488 , ;

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4-Chloro-5-sulfamoylanthranilic Acid Structure

4-Chloro-5-sulf...

CAS#:3086-91-7

Literature: Journal of the American Chemical Society, , vol. 81, p. 5508 Journal of the American Chemical Society, , vol. 82, p. 2731,2733,2734 US2952680 , ; US2910488 , ;

~%

4-Chloro-5-sulfamoylanthranilic Acid Structure

4-Chloro-5-sulf...

CAS#:3086-91-7

Literature: Journal of the American Chemical Society, , vol. 81, p. 5508 Journal of the American Chemical Society, , vol. 82, p. 2731,2733,2734

~29%

4-Chloro-5-sulfamoylanthranilic Acid Structure

4-Chloro-5-sulf...

CAS#:3086-91-7

Literature: Tetrahedron, , vol. 67, # 49 p. 9518 - 9521

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Articles10

More Articles
The use of HPLC to elucidate the metabolism and urinary excretion of furosemide and its metabolic products.

Acta Pharmacol. Toxicol. (Copenh.) 49(3) , 223-9, (1981)

Three principles for the use of HPLC with spectrophotometric detection to determine the concentration of furosemide and of 4-chloro-5-sulfamoyl anthranilic acid (CSA) were studied. A reversed phase mi...

The binding of furosemide to serum proteins in elderly patients: displacing effect of phenprocoumon.

Acta Pharmacol. Toxicol. (Copenh.) 47(3) , 202-7, (1980)

The percentual binding of furosemide (5 micrograms/ml) was slightly but significantly lower in serum from elderly patients than in serum from normal blood donors (96.5 +/- 0.7 versus 97.9 +/- 0.3). A ...

Furosemide accelerates gentamicin accumulation in cultured renal cells (LLC-PK1 cells).

Nephron 53(2) , 138-41, (1989)

Furosemide is known to potentiate gentamicin nephrotoxicity. The mechanism of potentiation is unclear. In our previous studies, we demonstrated that furosemide enhanced gentamicin accumulation in rabb...

 Synonyms

4-Chloro-5-sulfamoylanthranilic acid
2-AMINO-5-AMINOSULFONYL-4-CHLOROBENZOIC ACID
4-chloro-5-sulphamoyl anthranilic acid
Desfurylmethylfurosemide
Saluamine
2-amino-4-chloro-5-sulfamoyl-benzoic acid
Furosemide Related Compound B
EINECS 221-408-7
4-chloro-5-sulfamoyl-anthranilic acid
4-Chloro-5-sulfanilanthranilic acid