Crustacean Cardioactive Peptide CCAP

Modify Date: 2024-01-11 15:56:09

Crustacean Cardioactive Peptide CCAP Structure
Crustacean Cardioactive Peptide CCAP structure
 Common Name Crustacean Cardioactive Peptide CCAP
CAS Number 309247-84-5 Molecular Weight 959.10
Density N/A Boiling Point N/A
Molecular Formula C42H58N10O12S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Crustacean Cardioactive Peptide CCAP


Crustacean Cardioactive Peptide (CCAP) is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean Cardioactive Peptide (CCAP) also modulates the neuronal activity in other arthropods.

 Names

Name Crustacean Cardioactive Peptide CCAP

 Crustacean Cardioactive Peptide CCAP Biological Activity

Description Crustacean Cardioactive Peptide (CCAP) is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean Cardioactive Peptide (CCAP) also modulates the neuronal activity in other arthropods.
Related Catalog
In Vitro Ultrabithorax and Abdominal-A are not necessary for specification of the CCAP-interneurons, but are absolutely required to prevent the death by apoptosis of the CCAP-efferent neurons[2].
In Vivo CCAP, FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates, increase hemolymph flow velocity in the antennal space[1].
References

[1]. Suggs JM, et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219(Pt 15):2388-95.

[2]. Moris-Sanz M, et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4(9):1132-42.

 Chemical & Physical Properties

Molecular Formula C42H58N10O12S2
Molecular Weight 959.10
Storage condition 2-8℃
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