MMG 11

Modify Date: 2024-01-02 15:52:38

MMG 11 Structure
MMG 11 structure
Common Name MMG 11
CAS Number 313254-94-3 Molecular Weight 306.27
Density N/A Boiling Point N/A
Molecular Formula C15H14O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMG 11


MMG-11 is a potent and selective human TLR2 antagonist. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with an IC50 of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].

 Names

Name MMG-11

 MMG 11 Biological Activity

Description MMG-11 is a potent and selective human TLR2 antagonist. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with an IC50 of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].
Related Catalog
Target

TLR2

References

[1]. Grabowski M, et al. Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure-based virtual screening. Biochem Pharmacol. 2018 Aug;154:148-160.

 Chemical & Physical Properties

Molecular Formula C15H14O7
Molecular Weight 306.27
Storage condition -20°C
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